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抑制剂 & 化合物

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Cat. No. Product Name Target Signaling Pathways
T70062 Osteoprotegerin

Osteoprotegerin is a soluble secreted member of the tumor necrosis factor receptor superfamily, inhibiting osteoclastogenesis by interrupting the signaling between stromal cells and osteoclastic progenitor cells, leading to excess accumulation of bone and cartilage.

化合物

Osteoprotegerin
Cat.No: T70062
Synonym:
Target:
Cat. No. Product Name Species Expression System
TMPJ-01466 Osteoprotegerin Protein, Human, Recombinant (aa 22-401, His)

OPG,Tumor Necrosis Factor Receptor Superfamily Member 11B,OC...

Human HEK293 Cells
TNFRSF11B is a secreted protein, containing 2 death domains and 4 TNFR-Cys repeats. TNFRSF11B is a decoy receptor for the receptor activator of nuclear factor kappa B ligand (RANKL). By binding RANKL, TNFRSF11B inhibits nuclear kappa B (NF-κB) which is a central and rapid acting transcription factor for immune-related genes, and a key regulator of inflammation, innate immunity, and cell survival and differentiation. TNFRSF11B levels are influenced by voltage-dependent calcium channelsCav1.2. TNF...
TMPY-04509 Osteoprotegerin Protein, Mouse, Recombinant (hFc)

tumor necrosis factor receptor superfamily member 11b,Opg,TR...

Mouse HEK293 Cells
Osteoprotegerin Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 70.2 kDa and the accession number is O08712.
TMPJ-00607 RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (His)

Receptor activator of nuclear factor κ-B ligand,Osteopro...

Mouse HEK293 Cells
RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with N-6xHis tag. The predicted molecular weight is 30-35 KDa and the accession number is BAA97257.1.
TMPY-03323 Osteoprotegerin Protein, Rhesus, Recombinant (hFc)

tumor necrosis factor receptor superfamily member 11b,TNFRSF...

Rhesus HEK293 Cells
Osteoprotegerin Protein, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 65 kDa and the accession number is G7N005.
TMPY-01724 Osteoprotegerin Protein, Human, Recombinant (His)

OCIF,OPG,MGC29565,TR1,PDB5,tumor necrosis factor receptor su...

Human HEK293 Cells
Osteoprotegerin Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 45.3 kDa and the accession number is O00300.
TMPY-05262 Osteoprotegerin Protein, Human, Recombinant (hFc)

MGC29565,OPG,PDB5,tumor necrosis factor receptor superfamily...

Human Baculovirus Insect Cells
Osteoprotegerin Protein, Human, Recombinant (hFc) is expressed in Baculovirus insect cells with hFc tag. The predicted molecular weight is 70.3 kDa and the accession number is O00300.
TMPJ-00253 OPG Protein, Mouse, Recombinant (His)

Opg,Ocif,Tnfrsf11b,Osteoclastogenesis inhibitory factor,...

Mouse HEK293 Cells
Osteoprotegerin (OPG, Tnfrsf11b) is a secreted protein that regulates bone density. OPG is widely expressed and constitutively released as a homodimer by mesenchymal stem cells, fibroblasts and endothelial cells. Regulation of its expression by estrogen, parathyroid hormone and cytokines is complex and changes with age. OPG acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. TRAIL decreases the release of OPG from cells that express it, while OPG ...

重组蛋白

Osteoprotegerin Protein, Human, Recombinant (aa 22-401, His)
Cat.No: TMPJ-01466
Species: Human
Expression System: HEK293 Cells
Osteoprotegerin Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-04509
Species: Mouse
Expression System: HEK293 Cells
RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-00607
Species: Mouse
Expression System: HEK293 Cells
Osteoprotegerin Protein, Rhesus, Recombinant (hFc)
Cat.No: TMPY-03323
Species: Rhesus
Expression System: HEK293 Cells
Osteoprotegerin Protein, Human, Recombinant (His)
Cat.No: TMPY-01724
Species: Human
Expression System: HEK293 Cells
Osteoprotegerin Protein, Human, Recombinant (hFc)
Cat.No: TMPY-05262
Species: Human
Expression System: Baculovirus Insect Cells
OPG Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-00253
Species: Mouse
Expression System: HEK293 Cells
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