Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T1524 |
Nilotinib
尼洛替尼,尼罗替尼,Tasigna,AMN107 |
Bcr-Abl; Autophagy | Angiogenesis; Autophagy; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors |
Nilotinib (AMN107) 是一种 Bcr-Abl 酪氨酸激酶抑制剂,具有抗肿瘤活性。 | |||
T2147 |
Nilotinib monohydrochloride monohydrate
Nilotinib (monohydrochloride monohydrate),尼洛替尼盐酸盐一水合物,AMN107 (monohydrochloride monohydrate),尼罗替尼中间体 |
Bcr-Abl; Autophagy | Angiogenesis; Autophagy; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors |
Nilotinib monohydrochloride monohydrate (Nilotinib (monohydrochloride monohydrate)) 是酪氨酸酶抑制剂,有效抑制 BCR-ABL 及其突变体。 | |||
T22378 |
Nilotinib hydrochloride
AMN-107 HCl |
Bcr-Abl; Autophagy | Angiogenesis; Autophagy; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors |
Nilotinib hydrochloride(AMN-107 HCl) 是一种可口服的 Bcr-Abl 酪氨酸激酶抑制,具有抗肿瘤活性,可用于调节神经炎症和认知障碍,可用于研究慢性骨髓性白血病。 | |||
T68338 | Nilotinib hydrochloride dihydrate | ||
Nilotinib hydrochloride dihydrate is a small-molecule tyrosine kinase inhibitor approved for the treatment of imatinib-resistant chronic myelogenous leukemia. | |||
T19035 |
Nilotinib Acid
|
Others | Others |
Nilotinib Acid, an analog of Nilotinib, is usually used as a fluorescent probe or labeled chemical. | |||
T71068 |
Nilotinib dihydrochloride dihydrate
|
||
Nilotinib dihydrochloride dihydrate is a small-molecule tyrosine kinase inhibitor approved for the treatment of imatinib-resistant chronic myelogenous leukemia. | |||
T12224 |
Nilotinib-d6
AMN107 D6 |
Others | Others |
Nilotinib D6 is a deuterium labeled Nilotinib which is an orally available inhibitor of Bcr-Abl tyrosine kinase ,and with antineoplastic activity. | |||
T71144 | Nilotinib N-oxide | ||
Nilotinib N-oxide is a small-molecule tyrosine kinase inhibitor approved for the treatment of imatinib-resistant chronic myelogenous leukemia. | |||
T71142 |
Tebuconazole-d9
|
||
Tebuconazole-d9 is intended for use as an internal standard for the quantification of tebuconazole by GC- or LC-MS. Tebuconazole is a triazole fungicide that is active against both seed and foliar fungi. It inhibits 14α-demethylase isolated from U. maydis and S. bicolor with IC50 values of 0.05 and 0.16 nM, respectively. It inhibits the androgenic effect of the androgen receptor agonist DHT (IC20 = 2.89 µM) and is cytotoxic (EC20 = 38.9 µM) in an MDA-kb2 assay. Tebuconazole (50 and 100 mg/kg per... | |||
T71066 |
Cidofovir sodium
|
||
Cidofovir sodium is the salt form of Cidofovir, a Cytomegalovirus Nucleoside Analog DNA Polymerase Inhibitor that is an injectable antiviral medication primarily used as a treatment for cytomegalovirus (CMV) retinitis in people with AIDS. The mechanism of action of cidofovir is as a DNA Polymerase Inhibitor. The chemical classification of cidofovir anhydrous is Nucleoside Analog. | |||
T71581 |
SGX393
|
||
SGX393 is an inhibitor of the CML mutant Bcr-AblT315I, thereby preempting in vitro resistance when combined with nilotinib or dasatinib. |