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Cat. No.	Product Name	Target	Signaling Pathways
TP1140L	Neuropeptide Y (29-64), amide, human acetate	Neuropeptide Y Receptor	GPCR/G Protein; Neuroscience
	Neuropeptide Y (29-64), amide, human acetate 参与阿尔茨海默病 (AD) 并保护大鼠皮质神经元免受 β-淀粉样蛋白毒性。
T36446	Neuropeptide Y (human) (TFA)
	Neuropeptide Y (human) TFA, a compound implicated in Alzheimer's disease (AD), exhibits protective effects against β-Amyloid toxicity in rat cortical neurons.
T36445	Neuropeptide Y (3-36) (human, rat)
	Neuropeptide Y (3-36) (human, rat) is a metabolite of neuropeptide Y (NPY) generated by dipeptidyl peptidase-4 (DPP4). Known as a selective Y2 receptor agonist, Neuropeptide Y (3-36) (human, rat) effectively reduces the release of norepinephrine via the Y2 receptor[1][2].
TP1140	Neuropeptide Y (human) Human neuropeptide Y (29-64),Neuropeptide Y (29-64), amide, human
	Neuropeptide Y (29-64), amide, human is a biologically active 36-amino acid peptide.
T35599	Neuropeptide Y (3-36) (human, rat) (trifluoroacetate salt)
	Neuropeptide Y (NPY) (3-36) is a C-terminal fragment of NPY, a neuropeptide involved in controlling appetite, blood pressure, cardiac contractility, and intestinal secretion. NPY (3-36) is an endogenous peptide produced by cleavage of NPY by dipeptidyl peptidase 4 (DPP-4). It binds selectively to the NPY receptor Y2 (Ki = 0.41 nM in CHP 234 cells) over the Y1 receptor, where it does not bind at concentrations up to 1 μM. NPY (3-36) (0.1 nM) increases migration of human umbilical vein endothelial...
TP1081	Neuropeptide Y (13-36), amide, human Neuropeptide Y (13-36), human
	Neuropeptide Y (13-36), amide, human is a neuropeptide Y receptor agonist.
TP1985	[Leu31,Pro34]-Neuropeptide Y(human,rat) [Leu31,Pro34]-Neuropeptide Y (human, rat)
	High affinity neuropeptide Y Y1 receptor agonist (Ki = 0.39 nM). Also shows affinity for Y4 and Y5 receptors.
TP1338	Neuropeptide Y (29-64), amide, human TFA
	Neuropeptide Y (29-64), amide, human (TFA) is involved in Alzheimer's disease (AD) and protects rat cortical neurons against β-Amyloid toxicity.It is showed that Neuropeptide Y (29-64), amide, human (TFA) is able to protect cortical neurons from Aβ25-35 t
TP1059	Peptide YY (PYY) (3-36), human Peptide YY (3-36)	Neuropeptide Y Receptor	GPCR/G Protein; Neuroscience
	Peptide YY (PYY) (3-36), human (Peptide YY (3-36)) 是一种肠胃激素肽，可以激动Y2受体，具有降低食欲的功效。
T76358	Neuropeptide Y (1-24) (human)
	Neuropeptide Y (1-24) (human) 是一种神经肽，它能够抑制大鼠输精管电刺激引发的抽搐反应，同时在体内刺激 N-methyl-D-aspartate (NMDA) 促使大鼠海马背侧 CA3 区神经元激活。
T75730	[D-Arg25]-Neuropeptide Y (human)
	[D-Arg25]-Neuropeptide Y (human) ([D-Arg25] NPY) 是Y1受体的选择性激动剂。与阿尔茨海默病相关，该化合物能够保护老鼠皮质神经元免受淀粉样蛋白毒性的损害。
T75912	[Leu31,Pro34]-Neuropeptide Y(human,rat) TFA
	[Leu31,Pro34]-Neuropeptide Y(human,rat) TFA 是一种针对神经肽 YY1受体的特定激动剂，并亦能够激活Y4和Y5受体。该化合物能提高麻醉大鼠的血压并增加食物摄入。
TP1137L	Pancreatic Polypeptide (human) acetate	Neuropeptide Y Receptor	GPCR/G Protein; Neuroscience
	Pancreatic Polypeptide (human) acetate 是一种 C 末端酰胺化的 36 个氨基酸肽，可作为神经肽 Y (NPY) Y4/Y5 受体激动剂。
T10539	BIBO3304 TFA	Neuropeptide Y Receptor	GPCR/G Protein; Neuroscience
	BIBO3304 TFA 是一种可口服的、选择性的神经肽 Y(NPY) Y1受体高效拮抗剂，对人和大鼠 Y1 受体均具有高亲和力，IC50分别为 0.38 和 0.72 nM。
T69402	FR-226928
	FR-226928 is a potent antagonist of human neuropeptide Y Y5 receptors.
T76441	(Pro34)-Peptide YY (human)
	(Pro34)-Peptide YY (human) 是 Peptide YY/neuropeptide Y 受体的高度 Y1选择性全激动剂。
T68732	FR-226928 free base
	FR-226928 free base is a potent antagonist of human neuropeptide Y Y5 receptors.
T75899	CART(55-102)(human) TFA
	CART(55-102)(human) TFA，一种与瘦素和神经肽 Y 密切相关的人源饱腹感因子，具有显著的抑制食欲作用。
T75910	GR231118 TFA
	GR231118是神经肽Y的C末端类似物，作为人神经肽YY受体的高竞争性和相对选择性的拮抗剂（pKi=10.4），并对人类神经肽Y4受体显示出拮抗效果（pEC50=8.6；pKi=9.6），同时是对人及大鼠神经肽YY2与Y5受体的弱激动剂。此外，GR231118对小鼠神经肽YY6受体具有较高亲和力（pKi=8.8）。
T12623	(R)-JNJ-31020028	Others	Others
	(R)-JNJ-31020028 is a high affinity, selective brain penetrant antagonist of neuropeptide Y Y2 receptor(pIC50 values of 8.07, 8.22 and 8.21 for human, rat, and mouse Y2 receptor, respectively).
T15620	JNJ-5207787	Others	Others
	JNJ-5207787 is a penetrates the blood-brain barrier neuropeptide Y Y2 receptor (Y2) antagonist. It is >100-fold selective versus human Y1, Y4, and Y5 receptors. JNJ-5207787 suppresses the binding of peptide YY with pIC50s of 7.0 and 7.1 for the human Y2 r
T76356	Neuropeptide Y (2-36) (porcine)
	Neuropeptide Y (2-36) (porcine) 是一种具有 97.14% 与大鼠/人类同源性的猪源性神经肽。作为一种大鼠神经肽受体激动剂，其对Y5、Y2和Y1受体的EC50值为1.2, 1.6 和 3.4 nM，能显著增加食物摄入量，适用于肥胖和饮食失调研究。
TP1963	[cPP1-7,NPY19-23,Ala31,Aib32,Gln34]-hPancreatic Polypeptide cpp1-7-npy19-23-ala31-aib32-gln34-hpancreatic-polypeptide,[cPP1-7,NPY19-23,Ala31,Aib32,Gln34] - hPancreatic Polypeptide
	Potent, selective peptide agonist for the neuropeptide Y Y5 receptor (IC50 values for inhibition of NPY binding to human Y5, Y1, Y2 and Y4 receptors are 0.24, 530, > 500, and 51 nM respectively, Ki at Y5 = 0.1 - 0.15 nM). Stimulates food intake in vivo.
T76365	CART (1-39), Human, Rat
	CART (1-39), Human, Rat, 是一种由其1至39个残基构成的神经肽, 具有明显的减少食欲作用, 被认为是鼠类的饱腹因子, 并与瘦素及神经肽Y有着紧密的联系。它能有效抑制正常及饥饿状态下的摄食行为, 同时也能引发焦虑与压力相关的反应。
T35597	Neuromedin U-23 (rat) (trifluoroacetate salt)
	Neuromedin U-23 (NMU-23) is a neuropeptide involved in diverse biological processes, including smooth muscle contraction, energy homeostasis, and nociception.1It is an agonist of neuromedin-U receptor 1 (NMUR1; EC50= 0.17 nM for the human receptor in a calcium mobilization assay using HEK293 cells) and NMUR2 (EC50= ~1.4-2 nM for arachidonic acid release in CHO cells expressing the human receptor).2,3NMU-23 (1 μM) induces contractions in isolated rat colon smooth muscle strips.4It decreases body ...
T35406	α-MSH TFA
	α-Melanocyte-stimulating hormone (α-MSH) is a 13-amino acid peptide hormone produced by post-translational processing of proopiomelanocortin (POMC) in the pituitary gland, as well as in keratinocytes, astrocytes, monocytes, and gastrointestinal cells.1It is an agonist of melanocortin receptor 3 (MC3R) and MC4R that induces cAMP production in Hepa cells expressing the human receptors (EC50s = 0.16 and 56 nM, respectively).2α-MSH (100 pM) reducesS. aureuscolony formation andC. albicansgerm tube fo...

化合物

Neuropeptide Y (29-64), amide, human acetate

Cat.No: TP1140L

Target: Neuropeptide Y Receptor

Neuropeptide Y (human) (TFA)

Cat.No: T36446

Neuropeptide Y (3-36) (human, rat)

Cat.No: T36445

Neuropeptide Y (human)

Cat.No: TP1140

Synonym: Human neuropeptide Y (29-64),Neuropeptide Y (29-64), amide, human

Neuropeptide Y (3-36) (human, rat) (trifluoroacetate salt)

Cat.No: T35599

Neuropeptide Y (13-36), amide, human

Cat.No: TP1081

Synonym: Neuropeptide Y (13-36), human

[Leu31,Pro34]-Neuropeptide Y(human,rat)

Cat.No: TP1985

Synonym: [Leu31,Pro34]-Neuropeptide Y (human, rat)

Neuropeptide Y (29-64), amide, human TFA

Cat.No: TP1338

Peptide YY (PYY) (3-36), human

Cat.No: TP1059

Synonym: Peptide YY (3-36)

Target: Neuropeptide Y Receptor

Neuropeptide Y (1-24) (human)

Cat.No: T76358

[D-Arg25]-Neuropeptide Y (human)

Cat.No: T75730

[Leu31,Pro34]-Neuropeptide Y(human,rat) TFA

Cat.No: T75912

Pancreatic Polypeptide (human) acetate

Cat.No: TP1137L

Target: Neuropeptide Y Receptor

Cat.No: T10539

Target: Neuropeptide Y Receptor

Cat.No: T69402

(Pro34)-Peptide YY (human)

Cat.No: T76441

FR-226928 free base

Cat.No: T68732

CART(55-102)(human) TFA

Cat.No: T75899

Cat.No: T75910

(R)-JNJ-31020028

Cat.No: T12623

Target: Others

Cat.No: T15620

Target: Others

Neuropeptide Y (2-36) (porcine)

Cat.No: T76356

[cPP1-7,NPY19-23,Ala31,Aib32,Gln34]-hPancreatic Polypeptide

Cat.No: TP1963

Synonym: cpp1-7-npy19-23-ala31-aib32-gln34-hpancreatic-polypeptide,[cPP1-7,NPY19-23,Ala31,Aib32,Gln34] - hPancreatic Polypeptide

CART (1-39), Human, Rat

Cat.No: T76365

Neuromedin U-23 (rat) (trifluoroacetate salt)

Cat.No: T35597

Cat.No: T35406

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