Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TP1981L |
Neuropeptide S (Mouse) acetate
|
Neuropeptide Y Receptor | GPCR/G Protein; Neuroscience |
Neuropeptide S (Mouse) acetate 是一种生物活性肽。它作为 20 种氨基酸的神经递质/神经调节剂,可用于觉醒、焦虑、运动、摄食行为、记忆和药物成瘾的研究。 | |||
TP1982L |
Neuropeptide S (Rat) acetate
|
Neuropeptide Y Receptor | GPCR/G Protein; Neuroscience |
Neuropeptide S (Rat) acetate 是以前孤儿 G 蛋白偶联受体的内源性配体,现在称为 NPS 受体。它可用于神经系统疾病的研究。 | |||
TP1981 |
Neuropeptide S(Mouse)
Neuropeptide S (Mouse) |
||
Potent endogenous neuropeptide S receptor (NPSR) agonist (EC50 = 3 nM). Induces mobilization of intracellular Ca2+. Increases locomotor activity and wakefulness in mice. Also reduces anxiety-like behavior in mice. | |||
TP1982 |
Neuropeptide S(Rat)
Neuropeptide S (Rat) |
||
Potent endogenous neuropeptide S receptor (NSPR) agonist (EC50 = 3.2 nM). Increases locomotor activity and wakefulness in mice. Also reduces anxiety-like behavior in mice. | |||
TP1983 |
Neuropeptide S (human)
|
||
Potent endogenous neuropeptide S receptor agonist (EC50 = 9.4 nM). Increases locomotor activity and wakefulness in mice. Also reduces anxiety-like behavior in mice. | |||
TP1593 |
Neuropeptide S (human) (TFA)
|
||
Neuropeptide S human (TFA) is a potent endogenous neuropeptide S receptor agonist (EC50=9.4 nM). | |||
T17222 |
Velneperit
韦利贝特,S2367 |
Neuropeptide Y Receptor | GPCR/G Protein; Neuroscience |
Velneperit (S2367) 是一种有效且选择性的神经肽 Y (NPY) Y5 受体,有用于治疗肥胖症的研究潜力。 | |||
T75951 |
Neuropeptide S(Rat) TFA
|
||
Neuropeptide S(Rat) TFA, a robust endogenous agonist for the neuropeptide S receptor (NSPR) with an EC50 of 3.2 nM, enhances locomotor activity and promotes wakefulness while concurrently diminishing anxiety-like behavior in mice. | |||
T75950 |
Neuropeptide S(Mouse) TFA
|
||
Neuropeptide S(Mouse) TFA, an endogenous agonist for the neuropeptide S receptor (NPSR) with an EC50 value of 3 nM, plays a significant role in physiological processes by inducing the mobilization of intracellular Ca2+. This compound elevates locomotor activity and wakefulness, and simultaneously decreases anxiety-like behavior in mice. | |||
T22994 |
ML 154
|
Neuropeptide Y Receptor | GPCR/G Protein; Neuroscience |
ML154 是NPSR 的有效拮抗剂。ML154 在焦虑、成瘾和食物障碍方面具有研究的潜力。 | |||
T71321 |
(S)-VU0637120
|
Others | Others |
(S)-VU0637120 是一种选择性的神经肽 Y(4)R变构拮抗剂,可用于研究代谢疾病。 | |||
T23287 |
S 25585
|
Others | Others |
S 25585 is a neuropeptide Y (NPY) Y5 receptor antagonist. | |||
T12895 |
SHA 68
|
Neuropeptide Y Receptor | GPCR/G Protein; Neuroscience |
SHA 68 是一种有效且选择性的神经肽 S 受体 (NPSR) 非肽拮抗剂,对 NPSR Asn107和 NPSR Ile107的IC50分别为 22.0 和 23.8 nM,具有有限的血脑屏障渗透能力和用于神经痛的活性。 | |||
T81682 |
Neuromedin S(rat) TFA
|
||
Neuromedin S(rat) TFA是一种含有34个氨基酸的肽段,源自大鼠的Neuromedin S,它是一种从大鼠大脑中分离得到的神经肽,能够作为FM4/TGR-1的配体。 | |||
T81683 |
Neuromedin S (human)
|
||
Neuromedin S (human) 是包含33个氨基酸的神经肽,作为G 蛋白偶联受体 (GPCR) FM-4/TGR-1的内源性配体,在大脑中被鉴定,并对神经调节素 U (NMU) 受体 2 (NMUR2)调节体重稳态具有调控作用。 | |||
TP1513 |
Egg Laying Hormone, aplysia
|
||
Egg-laying hormone (ELH) is a neuropeptide synthesized by the bag cell neurons, Egg-laying hormone (ELH) induces egg laying and its correlated behavior in Aplysia californica. Egg-laying hormone (ELH) has been purified to homogeneity and Egg-laying hormon | |||
T35598 |
Neuromedin U-25 (human) (trifluoroacetate salt)
|
||
Neuromedin U (NMU) is a neuropeptide first demonstrated to drive smooth muscle contraction.1Translated as a 174 amino acid propeptide, NMU is cleaved to different lengths in different animals. It has diverse receptor-mediated rolesin vivo, as it regulates feeding, vasoconstriction, nociception, and bone remodeling and contributes to obesity, cancer and septic shock.2,2NMU-25 is the active form of NMU in humans. It binds with high affinity to receptors on human left ventricle and coronary artery ... | |||
T35597 |
Neuromedin U-23 (rat) (trifluoroacetate salt)
|
||
Neuromedin U-23 (NMU-23) is a neuropeptide involved in diverse biological processes, including smooth muscle contraction, energy homeostasis, and nociception.1It is an agonist of neuromedin-U receptor 1 (NMUR1; EC50= 0.17 nM for the human receptor in a calcium mobilization assay using HEK293 cells) and NMUR2 (EC50= ~1.4-2 nM for arachidonic acid release in CHO cells expressing the human receptor).2,3NMU-23 (1 μM) induces contractions in isolated rat colon smooth muscle strips.4It decreases body ... | |||
T35406 |
α-MSH TFA
|
||
α-Melanocyte-stimulating hormone (α-MSH) is a 13-amino acid peptide hormone produced by post-translational processing of proopiomelanocortin (POMC) in the pituitary gland, as well as in keratinocytes, astrocytes, monocytes, and gastrointestinal cells.1It is an agonist of melanocortin receptor 3 (MC3R) and MC4R that induces cAMP production in Hepa cells expressing the human receptors (EC50s = 0.16 and 56 nM, respectively).2α-MSH (100 pM) reducesS. aureuscolony formation andC. albicansgerm tube fo... |