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Search Results for " neuraminidase in 1 "

11

抑制剂 & 化合物

2

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T8555	Neuraminidase-IN-1 Novel NA Inhibitor,Compound Y-1	Others; Influenza Virus	Microbiology/Virology; Others
	Neuraminidase-IN-1 (Compound Y-1) 是一种神经氨酸酶抑制剂，其IC50值为 0.21 μM，具有抗H1N1流感病毒的活性。
T61509	Neuraminidase-IN-8
	Neuraminidase-IN-8 (Compound 6d) 是一种有效的神经氨酸酶 (neuraminidase) 抑制剂，其IC50值为 0.027 μM。Neuraminidase-IN-8 具有抗流感活性。
T60939	Neuraminidase-IN-6
	Neuraminidase-IN-6 (Compound 5c) 是1,3,4-triazole-3-acetamide 的衍生物。Neuraminidase-IN-6 是神经氨酸酶的有效抑制剂，IC50值为 0.11 μM。神经氨酸酶 (NA) 是抗流感药物开发的理想靶点。
T74774	Neuraminidase-IN-16
	Neuraminidase-IN-16 (Compound 43b) 是一种有效的神经氨酸酶 (neuraminidase) 抑制剂，对 H5N1、H5N8、H1N1、H3N2、H5N1–H274Y 和 H1N1–H274Y 的神经氨酸酶抑制作用的 IC50分别为 0.031、0.15、0.25、0.60、0.63 和 10.08 μM。
T61557	Influenza A virus-IN-4
	Influenza A virus-IN-4 (compound 23b), a derivative of Oseltamivir, is a highly effective neuraminidase inhibitor. It exerts potent inhibitory effects on influenza viruses [1].
T78675	Neuraminidase-IN-13	Influenza Virus	Microbiology/Virology
	Neuraminidase-IN-13 (Compound 10) 为神经氨酸酶抑制剂，展现抗病毒功效及低细胞毒性。该化合物显著抑制Vero细胞中NDV感染，其作用机制为阻断病毒颗粒从受感染细胞的释放。
T61394	Neuraminidase-IN-5
	Neuraminidase-IN-5 (Compound 5b) 是一种有效的 neuraminidase 抑制剂，IC50为 0.02 μM。神经氨酸酶（NA）是开发抗流感药物的有希望的靶点。Neuraminidase-IN-5 是一种二氢呋喃香豆素衍生物化合物。
T76172	Neuraminidase
	Neuraminidase（Exo-α-sialidase）为一种常用于生化研究的外唾液酸酶，能够在唾液酸（N-acetylneuraminic）与临近糖残基间切断α-酮甙键（α-ketosidic）。该酶源自黏膜病原体，作为一种调整宿主感染反应的毒力因子。
T74766	Neuraminidase-IN-12
	NDV-IN-1 是一种具有高神经氨酸酶抑制活性的抗病毒剂。 NDV-IN-1 对新城疫病毒 (NDV) 具有体外抑制活性。NDV-IN-1 通过阻止病毒颗粒从感染细胞中释放出来，显著抑制 Vero 细胞的 NDV 感染。
T37295	Ganglioside GM1 Asialo Mixture
	Ganglioside GM1 asialo is a component of cellular lipid rafts and can be formed by the cleavage of the sialic acid residue from ganglioside GM1 by neuraminidase. Ganglioside GM1 asialo is a glycolipid receptor for P. aeruginosa flagellin and stimulates defensive responses in host cells, including extracellular ATP release, calcium mobilization, and ERK1/2 phosphorylation when stimulated by flagellin and an anti-ganglioside GM1 asialo antibody. The percentage of ganglioside GM1 asialo-positive na...
T38118	Zanamivir-13C,15N2 Zanamivir-13C,15N2
	Zanamivir-13C,15N2is intended for use as an internal standard for the quantification of zanamivir by GC- or LC-MS. Zanamivir is a sialic acid analog that inhibits neuraminidase release of newly replicated influenza virus particles.1It has been shown to selectively inhibit the growth of influenza A and B viruses in plaque reduction assays with IC50values ranging from 5 to 14 nM and to directly inhibit influenza A and B virus neuraminidases with IC50values ranging from 0.6 to 7.9 nMin vitro. Intra...

化合物

Neuraminidase-IN-1

Cat.No: T8555

Synonym: Novel NA Inhibitor,Compound Y-1

Target: Others, Influenza Virus

Neuraminidase-IN-8

Cat.No: T61509

Neuraminidase-IN-6

Cat.No: T60939

Neuraminidase-IN-16

Cat.No: T74774

Influenza A virus-IN-4

Cat.No: T61557

Neuraminidase-IN-13

Cat.No: T78675

Target: Influenza Virus

Neuraminidase-IN-5

Cat.No: T61394

Neuraminidase

Cat.No: T76172

Neuraminidase-IN-12

Cat.No: T74766

Ganglioside GM1 Asialo Mixture

Cat.No: T37295

Zanamivir-13C,15N2

Cat.No: T38118

Synonym: Zanamivir-13C,15N2

Cat. No.	Product Name	Target	Signaling Pathways
TL0005	3,5-O-Dicaffeoylquinic acid Isochlorogenic Acid A,(-)-3,5-二咖啡酰奎宁酸,(-)-3,5-Dicaffeoyl quinic acid,3,5-Dicaffeoylquinic Acid	Others	Others
	3,5-O-Dicaffeoylquinic acid (Isochlorogenic Acid A) 能够改善由三甲基锡诱导的学习和记忆缺陷。
TN4108	Ganoderic acid Z	Antifection	Microbiology/Virology
	The binding affinities of ganoderic acid DM and ganoderic acid Z (ÎGbind, -16.83 and-10.99 kcal mol-1) are comparable to that of current commercial drug oseltamivir (-23.62 kcal mol-1);Ganoderic acid DM is a potential source of anti-influenza ingredient, with novel binding pattern and advantage over oseltamivir, it has steric hindrance on the 150 cavity of N1 protein, and exerts activities across the H274Y and N294S mutations, is the attractive candidates of novel neuraminidase (NA) inhibitors....

天然产物

3,5-O-Dicaffeoylquinic acid

Cat.No: TL0005

Synonym: Isochlorogenic Acid A,(-)-3,5-二咖啡酰奎宁酸,(-)-3,5-Dicaffeoyl quinic acid,3,5-Dicaffeoylquinic Acid

Target: Others

Ganoderic acid Z

Cat.No: TN4108

Target: Antifection

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