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Cat. No. Product Name Target Signaling Pathways
T12179 Nav1.1 activator 1

Others Others
Nav1.1 activator 1 is a highly potent activator of Nav1.1 with BBB penetration.
T36813 Lu AE98134

Lu AE98134, an activator of voltage-gated sodium channels, acts as a partly selective Nav1.1 channels positive modulator. Lu AE98134 also increases the activity of Nav1.2 and Nav1.5 channels but not of Nav1.4, Nav1.6 and Nav1.7 channels. Lu AE98134 can be used to analyze pathophysiological functions of the Nav1.1 channel in various central nervous system diseases, including cognitive restoring in schizophrenia, et al[1].
T80431 δ-Theraphotoxin-Hm1a toxin

Sodium Channel Membrane transporter/Ion channel
δ-Theraphotoxin-Hm1a毒素是一种针对Nav1.1通道的选择性激活剂,能够诱发疼痛反应和增强触觉敏感度,常用于研究肠易激综合征。
T80188 Hm1a

Sodium Channel Membrane transporter/Ion channel
Hm1a为一种具有多个二硫键的蜘蛛毒肽,兼作NaV1.1激活剂。在Dravet综合征(DS)小鼠模型中,Hm1a能够修复受损的抑制性中间神经元功能。

化合物

Nav1.1 activator 1
Cat.No: T12179
Synonym:
Target: Others
Lu AE98134
Cat.No: T36813
Synonym:
Target:
δ-Theraphotoxin-Hm1a toxin
Cat.No: T80431
Synonym:
Target: Sodium Channel
Hm1a
Cat.No: T80188
Synonym:
Target: Sodium Channel
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