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Cat. No. Product Name Target Signaling Pathways
T2041 PD153035

NSC 669364,SU-5271,ZM 252868,AG1517

EGFR Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
PD153035 (NSC-669364) 是一种EGFR 抑制剂,Ki 和IC50值分别为6和25 pM。
T1761 PD153035 hydrochloride

ZM 252868 HCl,AG 1517,Tyrphostin AG 1517,SU 5271,PD153035 HCl,ZM 252868

EGFR Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
PD153035 hydrochloride (ZM 252868) 是有效地EGFR 抑制剂,Ki 和IC50值分别为6和25 pM。
T69055 PD153035 nitrate

PD153035 is a ATP-competitive EGFR inhibitor with an IC50 and Ki of 25 and 6 pM. PD153035 effectively blocks the enhancement of mitogenesis, induction of early gene expression, and oncogenic transformation that occur in response to EGF receptor stimulation. With human fibroblasts and epidermoid carcinoma cells, PD153035 at nanomolar concentrations rapidly inhibits EGFR autophosphorylation. With breast and ovarian cancer cells, PD153035 not only blocks cell growth via inhibition of EGFR, but also...

化合物

PD153035
Cat.No: T2041
Synonym: NSC 669364,SU-5271,ZM 252868,AG1517
Target: EGFR
PD153035 hydrochloride
Cat.No: T1761
Synonym: ZM 252868 HCl,AG 1517,Tyrphostin AG 1517,SU 5271,PD153035 HCl,ZM 252868
Target: EGFR
PD153035 nitrate
Cat.No: T69055
Synonym:
Target:
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