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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T3275 |
Nefazodone hydrochloride
Dutonin,MJ-13754-1,Serzone,BMY-13754-1,BMY-13754,萘法唑酮盐酸盐 |
5-HT Receptor; Adrenergic Receptor | GPCR/G Protein; Neuroscience |
Nefazodone hydrochloride (Serzone) 是一种强效和选择性的5HT2A 拮抗剂,Ki 为5.8 nM,对 5-HT 和去甲肾上腺素摄取具有中度抑制作用,IC50分别为 290 和 300 nM。它是一种苯哌嗪类抗抑郁药,具有微弱的 α-肾上腺素阻断活性,用于治疗抑郁症、攻击性行为和恐慌症。 | |||
T21451 |
Nefazodone
Nefadar,Dutonin,Serzone |
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Nefazodone is an antidepressant. It has low affinity for the serotonin (200 nM), dopamine (360 nM), and norepinephrine (360 nM) transporters, and therefore acts as a weak serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI). |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPJ-01061 |
Nucleobindin-2 Protein, Human, Recombinant
NUCB2,NEFA,Gastric cancer antigen Zg4,Nesfatin-1,Pr... |
Human | E. coli |
Nesfatin-1 is a metabolic polypeptide encoded in the N-terminal region of the precursor protein, Nucleobindin2 (NUCB2). Nesfatin-1 is a neuropeptide produced in the hypothalamus of mammals. It participates in the regulation of hunger and fat storage. Nesfatin-1 is also expressed in other areas of the brain, and in pancreatic islets β-cells, gastric endocrine cells and adipocytes. Nesfatin-1 suppresses food intake and can regulate energy metabolism in a Leptin independent manner. Nesfatin-1 may ... |