Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T19032 |
Nitro blue tetrazolium chloride
NBT,氯化硝基四氮唑兰 |
NO Synthase | Immunology/Inflammation |
Nitro blue tetrazolium chloride (NBT) 是一种脱氢酶底物,能够与碱性磷酸酶底物 BCIP 一起用于 western blotting 和免疫组化染色。 | |||
T68570 | TPI-287 | ||
TPI 287 is a synthetic, third generation taxane with potential antineoplastic activity. TPI 287 binds to tubulin and stabilizes microtubules, resulting in inhibition of microtubule assembly/disassembly dynamics, cell cycle arrest at the G2/M phase, and apoptosis. | |||
T63275 | NBTIs-IN-4 | ||
NBTIs-IN-4 能够作用于多种革兰氏阳性病原体,具有显著的抗菌作用,对 DNA 旋转酶和拓扑异构酶 IV 表现出抑制作用,具有低耐药率。 | |||
T12191 |
NBTGR
|
AChR | Neuroscience |
NBTGR is a potent nucleoside transport inhibitor(adenosine uptake ,Ki of 70 nM). | |||
T62868 |
NBTIs-IN-5
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NBTIs-IN-5 (Compound 5r) 是一种 NBTI (新型细菌拓扑异构酶抑制剂) DNA gyrase 抑制剂,作用于 Mycobacterium abscessus(Mabs) DNA 促旋酶 (IC50: 1.5 μM)。NBTIs-IN-5 对 Mabsbamboo 细菌生长表现出抑制作用 (MIC90: 0.4 μM)。 | |||
T36003 | 1(R)-(Trifluoromethyl)oleyl alcohol | ||
1(R)-(Trifluoromethyl)oleyl alcohol is an analog of oleic acid .1It inhibits ferroptosis induced by erastin in primary fibroblasts isolated from patients with Friedreich ataxia, a neuro- and cardiodegenerative disorder characterized by loss or impaired activity of frataxin (FXN), when used at concentrations of 5, 10, or 20 μM. 1(R)-(Trifluoromethyl)oleyl alcohol (5 μM) reduces lipid peroxidation induced byFXNsiRNA knockdown in NBT human myoblasts. 1.Cotticelli, M.G., Forestieri, R., Xia, S., et ... | |||
T36593 |
TEI-9648
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TEI-9648, a Vitamin D3 Lactone analogue, is a potent and specific vitamin D receptor (VDR) antagonist. TEI-9648 inhibits VDR/VDRE-mediated genomic actions of 1α,25(OH)2D3. TEI-9648 also inhibits HL-60 cell differentiation induced by of 1α,25(OH)2D3. TEI-9648 has the potential for bone metabolism research[1][2]. TEI-9648 (10-1000 nM) dose-dependently blocks the reciprocal changes of CD11b and CD71 expression associated with HL-60 cell differentiation induced by 1α,25(OH)2D3[1]. TEI-9648 has cons... |