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3

抑制剂 & 化合物

3

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T28870	Strontium Malonate NBS-101,NBS 101,NBS101
	Strontium Malonate, a calcium-sensing receptor agonist, is used potentially for the treatment of postmenopausal osteoporosis.
T2477	UNBS5162 UNBS 5162,UNBS-5162	CXCR; Autophagy	Autophagy; GPCR/G Protein; Immunology/Inflammation
	UNBS5162 (UNBS-5162) 是一种新型萘酰亚胺，可降低实验性前列腺癌中 CXCL 趋化因子的表达。它是一种广谱趋化因子配体CXCL 拮抗剂，具有抗肿瘤活性。
T29060	UNBS-1450 UNBS 1450,UBS1450,UBS-1450,UBS 1450
	UNBS-1450 is a sodium channel antagonist. UNBS-1450 is a hemi-synthetic cardenolide derived from 2″-oxovorusharin, it is effective against various cancer cell types with an excellent differential toxicity. At low nanomolar concentrations, UNBS-1450 induce

化合物

Strontium Malonate

Cat.No: T28870

Synonym: NBS-101,NBS 101,NBS101

Cat.No: T2477

Synonym: UNBS 5162,UNBS-5162

Target: CXCR, Autophagy

Cat.No: T29060

Synonym: UNBS 1450,UBS1450,UBS-1450,UBS 1450

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-04467	NME1 Protein, Human, Recombinant (His) NME/NM23 nucleoside diphosphate kinase 1,NB,NDPK-A,NM23-H1,<...	Human	E. coli
	NME1, also known as Nucleoside Diphosphate Kinase A (NDK-A), or NM23-H1, belongs to the NDK family. NM23-H1 is known to have a metastasis suppressive activity in many tumor cells. Recent studies have shown that the interacting proteins with NM23-H1 which mediate cell proliferation, may act as modulators of the metastasis suppressor activity. The interacting proteins with NM23-H1 can be classified into 3 groups. The first group of proteins can be classified as upstream kinases of NM23-H1 such as ...
TMPH-01697	MORC3 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Nuclear factor which forms MORC3-NBs (nuclear bodies) via an ATP-dependent mechanism. Sumoylated MORC3-NBs can also associate with PML-NBs. Recruits TP53 and SP100 to PML-NBs, thus regulating TP53 activity. Binds RNA in vitro. May be required for influenza A transcription during viral infection. Histone methylation reader which binds to non-methylated (H3K4me0), monomethylated (H3K4me1), dimethylated (H3K4me2) and trimethylated (H3K4me3) 'Lys-4' on histone H3. The order of binding preference is ...
TMPH-02855	PML Protein, Mouse, Recombinant (His & Myc)	Mouse	E. coli
	Functions via its association with PML-nuclear bodies (PML-NBs) in a wide range of important cellular processes, including tumor suppression, transcriptional regulation, apoptosis, senescence, DNA damage response, and viral defense mechanisms. Acts as the scaffold of PML-NBs allowing other proteins to shuttle in and out, a process which is regulated by SUMO-mediated modifications and interactions. Positively regulates p53/TP53 by acting at different levels (by promoting its acetylation and phosp...

重组蛋白

NME1 Protein, Human, Recombinant (His)

Cat.No: TMPY-04467

Species: Human

Expression System: E. coli

MORC3 Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-01697

Species: Human

Expression System: E. coli

PML Protein, Mouse, Recombinant (His & Myc)

Cat.No: TMPH-02855

Species: Mouse

Expression System: E. coli

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