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Cat. No.	Product Name	Target	Signaling Pathways
T27135	DDD85646 DDD 85646,DDD-85646	Parasite	Microbiology/Virology
	DDD85646 是 T. brucei N-myristoyltransferase 的抑制剂，Ki 为 1.44 nM，IC50 为 2 nM，EC50 为 2 nM。 hNMT 的 IC50 为 4 nM。
T23973	DDD100097 DDD 100097,DDD-100097	Others	Others
	DDD100097 是一种有效的 N-肉豆蔻醇转移酶抑制剂，对布氏锥虫具有潜在的抑制作用，可用于研究神经系统疾病。
T23477	tris(dibenzylideneacetone)dipalladium Tris DBA,三(二亚苄基丙酮)二钯	Others	Others
	tris(dibenzylideneacetone)dipalladium (Tris DBA) 是一种 N-myristoyltransferase-1 (NMT-1) 抑制剂。
T63788	PCLX-001	Others	Others
	PCLX-001 is a small-molecule compound that acts as an orally active inhibitor of N-myristoyltransferase (NMT), specifically targeting NMT1 and NMT2 with IC50 values of 5 nM and 8 nM, respectively. This compound demonstrates anti-tumor effects and effectively inhibits the early signaling of B-cell receptor (BCR). Consequently, PCLX-001 is a valuable tool for researching B-cell malignancies [1] [2].
T28596	RO-09-4609 RO 09-4609,RO09-4609,RO 094609,RO-094609
	RO-09-4609 is a potent and selective inhibitor of Candida albicans N-myristoyltransferase (CaNmt).
T28701	SC-58272 SC58272
	SC-58272 is an inhibitor of N-myristoyltransferase (Nmt), a target for anti-fungal and anti-viral therapy.
T70753	PF00349412
	PF00349412 is a selective inhibitor of protozoan protein N-myristoyltransferases. Inhibition of N-myristoyltransferase has been validated pre-clin. as a target for the treatment of fungal and trypanosome infections, using species-specific inhibitors.
T35691	Myristoyl Coenzyme A (hydrate)
	Myristoyl coenzyme A (myristoyl-CoA) is a derivative of CoA that contains the long-chain fatty acid myristic acid . It is a substrate for N-myristoyltransferase during myristoylation, a process that adds a myristoyl group to proteins either during translation to modify protein activity or post-translationally in apoptotic cells. It is also a substrate in the de novo synthesis of phosphatidylinositol .
T68562	FTR-1335
	FTR1335 is a CaNMT inhibitor (IC50 = 0.49 nM) with good fungal selectivity. CaNMT inhibitors are fungicidal and show antifungal activity against Candida (especially fluconazole-resistant strains). They function by inhibiting N-myristoyltransferase (NMT), which catalyzes the transfer of a C14 fatty acif from myristoyl-CoA to the N-terminal of glycine in many fungal proteins. Without this process, fungi can die. This process also occurs in humans, and as such selectivity is an important characteri...