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Search Results for " myostatin "

Targets Recommended: Opioid Receptor

2

抑制剂 & 化合物

5

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T77445	Apitegromab SRK-015	Opioid Receptor	Endocrinology/Hormones; GPCR/G Protein; Neuroscience
	Apitegromab (SRK-015) 是一种新型肌肉生长抑制素抑制剂，是一种靶向肌肉生长抑制素前体的抗体,可用于研究脊髓性肌萎缩症在内的神经肌肉疾病。
T40481	IBS008738
	IBS008738, a potent TAZ activator, stabilizes TAZ, elevates the unphosphorylated TAZ level, enhances the interaction of MyoD with the myogenin promoter, upregulates gene transcription regulated by MyoD, and competes with myostatin in C2C12 cells. Additionally, IBS008738 promotes myogenesis in C2C12 cells and facilitates muscle repair in a model of muscle injury.

化合物

Cat.No: T77445

Synonym: SRK-015

Target: Opioid Receptor

Cat.No: T40481

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-04534	GDF-8 Protein, Mouse, Recombinant (hFc) 骨肉瘤源生长因子,Cmpt,myostatin,Gdf8	Mouse	HEK293 Cells
	GDF-8 / Myostatin / MSTN is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. GDF-8 / Myostatin / MSTN is highly expressed in skeletal muscle, and myostatin loss-of-function le...
TMPJ-00663	GDF-8 Protein, Human/Mouse/Rat, Recombinant 骨肉瘤源生长因子,Gdf8,Mstn,GDF-8,Growth/differentiation factor 8,	Human,Mouse,Rat	HEK293 Cells
	Growth/differentiation factor 8(Mstn, GDF-8) is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. It is expressed specifically in developing and adult skeletal muscle. It exists as a homodimer, and interacts with WFIKKN2, leading to inhibit its activity. This protein can act specifically a...
TMPJ-00713	GDF-11 Protein, Human, Recombinant Growth/differentiation factor 11,Bone morphogenetic protein ...	Human	HEK293 Cells
	Growth/differentiation factor 11(GDF-11) is a secreted protein, which belongs to the transforming growth factor beta superfamily. GDF-11 controls anterior-posterior patterning by regulating the expression of Hox genes. The secreted signal acts globally to specify positional identity along the anterior/posterior axis during development. GDF11 has been shown to suppress neurogenesis through a pathway similar to that of myostatin, including stopping the progenitor cell-cycle during G-phase. The si...
TMPY-01814	GASP-1/WFIKKN2 Protein, Human, Recombinant (His) WFIKKNRP,GASP-1,hGASP-1,WFDC20B,WAP, follistatin/kazal, immu...	Human	HEK293 Cells
	WAP, kazal, immunoglobulin, kunitz and NTR domain-containing protein 2, also known as Growth and differentiation factor-associated serum protein 1, WAP, follistatin, immunoglobulin, kunitz and NTR domain-containing-related protein, WFIKKN-related protein, WFIKKN2 and GASP1, is a secreted protein that belongs to the WFIKKN family. WFIKKN2 contains two BPTI/Kunitz inhibitor domains, one Ig-like C2-type (immunoglobulin-like) domain, one Kazal-like domain, one NTR domain and one WAP domain. WFIKKN2 ...
TMPK-00751	FSTL3 Protein, Human, Recombinant (His) FSTL3,FLRGFSRP,Follistatin-like 3,FLRG	Human	HEK293 Cells
	Follistatin-like 3 (FSTL3) is a novel cytokine that regulates insulin sensitivity and counteracts activin/myostatin signalling. In the present study, regulation of FSTL3 in renal dysfunction was investigated in both human chronic kidney disease (CKD) and acute kidney dysfunction (AKD). Furthermore, mFSTL3 expression was analysed in insulin-sensitive tissues in a mouse model of CKD.

重组蛋白

GDF-8 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-04534

Species: Mouse

Expression System: HEK293 Cells

GDF-8 Protein, Human/Mouse/Rat, Recombinant

Cat.No: TMPJ-00663

Species: Human,Mouse,Rat

Expression System: HEK293 Cells

GDF-11 Protein, Human, Recombinant

Cat.No: TMPJ-00713

Species: Human

Expression System: HEK293 Cells

GASP-1/WFIKKN2 Protein, Human, Recombinant (His)

Cat.No: TMPY-01814

Species: Human

Expression System: HEK293 Cells

FSTL3 Protein, Human, Recombinant (His)

Cat.No: TMPK-00751

Species: Human

Expression System: HEK293 Cells

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