Cat. No. | Product Name | Target | Signaling Pathways |
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T35964 |
MitoTEMPO hydrate
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MitoTEMPO is a mitochondria-targeted superoxide dismutase mimetic that possesses superoxide and alkyl radical scavenging properties.[1] This compound combines the antioxidant piperidine nitroxide TEMPO with the lipophilic cation triphenylphosphonium, which allows it to pass through lipid bilayers and accumulate in mitochondria. Mitochondrial targeting of superoxide scavenging via mitoTEMPO has been examined for potential therapeutic benefit to a variety of mitochondrial dysfunctions arising from... | |||
T19428 |
Mito-TEMPO
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Reactive Oxygen Species; Mitochondrial Metabolism | Immunology/Inflammation; Metabolism; NF-κB |
Mito-TEMPO 是一种线粒体靶向超氧化物歧化酶的模拟物。Mito-TEMPO 可以清除超氧化物和烷基自由基,防止线粒体的氧化、坏死和凋亡。 | |||
T35965 |
MitoTEMPOL
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MitoTEMPOL is a mitochondria-targeting superoxide dismutase mimetic that reduces mitochondrial O2- to H2O2. Like the related compound MitoTEMPO , MitoTEMPOL combines an antioxidant moiety (here, TEMPOL, also known as 4-hydroxy-TEMPO) with the lipophilic cation triphenylphosphonium, which allows it to pass through lipid bilayers and accumulate in mitochondria. MitoTEMPOL has been used to elucidate the role of mitochondria-derived superoxide in mitochondrial, cellular, and whole animal signaling. |