Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T8308 |
NL-1
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Mitochondrial Metabolism; Autophagy | Autophagy; Metabolism |
NL-1 是一种mitoNEET 抑制剂,具有抗白血病作用。它抑制 REH 和 REH/Ara-C 细胞生长,IC50分别为 47.35 µM 和 56.26 µM。 | |||
T24905 |
TT01001
TT-01001,TT 01001,Ethyl 4-(3-(3,5-dichlorophenyl)thioureido)piperidine-1-carboxylate |
Mitochondrial Metabolism | Metabolism |
TT01001 (Ethyl 4-(3-(3,5-dichlorophenyl)thioureido)piperidine-1-carboxylate) 是 mitoNEET 的选择性激动剂,通过改善线粒体功能障碍来减少氧化应激损伤和神经元凋亡。 TT01001可用于治疗 II 型糖尿病的研究。 | |||
T36517 |
Resveratrol-3-O-sulfate sodium
|
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Resveratrol-3-O-sulfate is a metabolite of resveratrol . In U-937 cells stimulated with LPS, resveratrol-3-O-sulfate (1 μM) decreases the expression of IL-1α, IL-1β, and IL-6 by 61.2, 76.6, and 42.2%, respectively, and decreases the release of TNF-α and IL-6 to similar levels as resveratrol. It has antioxidant activity in a Trolox assay, dose-dependently decreases growth of Caco-2 colorectal adenocarcinoma cells when used at concentrations ranging from 10 to 100 μM, and induces apoptosis at conc... |