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Cat. No. | Product Name | Target | Signaling Pathways |
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T23581 |
2-Methylthioadenosine diphosphate trisodium
2 Methylthio ADP,2MeSADP,2-Methylthio-ADP,2 MeS ADP,2-MeS-ADP |
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2-MeS-ADP is a purinergic agonist that acts by displaying selectivity for P2Y1, P2Y12, and P2Y13 receptors and inhibiting cAMP accumulation. | |||
TNU0255 |
2-Methylthioadenosine
|
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Nucleoside Derivatives - 2-Modified purine nucleosides; Drugs and Inhibitors; Platelet ADP receptor | |||
T22496 |
2-Methylthio-ATP tetrasodium
2-Methylthioadenosine triphosphate tetrasodium salt,2-methylthio-atp-tetrasodium |
Others | Others |
P2 purinoceptor agonist | |||
TNU0160 |
N6-Methyl-2-methylthioadenosine
|
Others | Others |
N6-Methyl-2-methylthioadenosine 是硫甲基化保护的核苷酸,可用于合成核苷衍生物。 | |||
T14141 |
AGI-24512
|
Others; Methionine Adenosyltransferase (MAT) | Chromatin/Epigenetic; Others |
AGI-24512 是一种甲硫氨酸腺苷转移酶 2A 抑制剂,在体外能够阻断 MTAP 缺失的癌细胞的生长,可用于研究癌症。 | |||
TNU0256 |
2-Cyanomethylthioadenosine
|
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2-Cyanomethylthioadenosine is a Nucleoside Derivative - 2-Modified purine nucleoside. | |||
TQ0008 |
MT-DADMe-ImmA
Methylthio-DADMe-Immucillin A,MTDIA |
Others | Others |
MT-DADMe-ImmA (MTDIA) 是一种人5'-甲硫基腺苷磷酸化酶的抑制剂 (MTAP)(Ki:90 pM)。 | |||
T12908 |
SIBA
5'-Deoxy-5'-isobutylthioadenosine,5'-Isobutylthioadenosine,5ˊ-异丁硫基-5ˊ-脱氧腺苷 |
Nucleoside Antimetabolite/Analog; HSV | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology |
SIBA (5'-Deoxy-5'-isobutylthioadenosine) 是 SAH 的合成类似物,可作为 S-腺苷甲硫氨酸介导的甲基转移的抑制剂。它干扰多种酶活性,可逆地阻断单纯疱疹病毒 1 型病毒的繁殖。 | |||
T31672 |
Erythrofuranosyladenine
9-β-D-Erythrofuranosyladenine,ETA |
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Erythrofuranosyladenine(9-beta-D-Erythrofuranosyladenine, ETA) is a nontoxic MTAP substrate. Erythrofuranosyladenine is an effective salvage agent for methylthioadenosine phosphorylase–selective therapy of T-cell acute lymphoblastic leukemia with L-alanos |
Cat. No. | Product Name | Target | Signaling Pathways |
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T8227 |
5'-Methylthioadenosine
Methylthioadenosine,5-脱氧-5-甲硫腺苷,5'-(Methylthio)-5'-deoxyadenosine,5'-Deoxy-5'-(methylthio)adenosine,5'-S-Methyl-5'-thioadenosine |
Endogenous Metabolite | Metabolism |
5'-Methylthioadenosine (Methylthioadenosine) 是由 S-腺苷蛋氨酸在多胺合成过程中生成的核苷,通过抑制肿瘤细胞增殖、侵袭和诱导细胞凋亡来抑制肿瘤,同时控制肿瘤组织的炎症微环境。 |