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Cat. No. Product Name Target Signaling Pathways
T80477 Muscarinic toxin 3

MT3

Adrenergic Receptor GPCR/G Protein; Neuroscience
Muscarinic toxin 3 (MT3) 是高效的非竞争性mAChR及adrenoceptors拮抗剂,对M1、M4、α1A、α1B、α1D、α2A、α2B、α2C受体展示出不同程度的选择性,其pIC50值分别为6.71、8.79、8.86、7.57、8.13、8.49、6.5、7.29。该化合物具有显著的肾上腺素受体抑制活性。
T63859 DNMT3A-IN-1

DNMT3A-IN-1 是选择性的、有效的 DNMT3A 抑制剂。 DNMT3A-IN-1 对 DNMT3A 表现出抑制活性,其 KI 的范围为 9.16-18.85 μM (AdoMet) 和 11.37-23.34 μM (poly dI-dC)。
T4093 Fabomotizole hydrochloride

Afobazole hydrochloride,CM346 hydrochloride

MAO Metabolism; Neuroscience
Fabomotizole hydrochloride (CM346 hydrochloride) 是一种具有抗焦虑和神经保护作用的化合物。
T70073 Fabomotizole dihydrochloride

Fabomotizole, also known as Afobazole, Obenoxazine and CM346, is an anxiolytic drug launched in Russia in the early 2000s. It produces anxiolytic and neuroprotective effects without any sedative or muscle relaxant actions. Its mechanism of action remains poorly defined however, with GABAergic, NGF- and BDNF-release-promoting, MT1 receptor agonism, MT3 receptor antagonism, and sigma agonism suggested as potential mechanisms. Fabomotizole was shown to inhibit MAO-A reversibly and there might be al...

化合物

Muscarinic toxin 3
Cat.No: T80477
Synonym: MT3
Target: Adrenergic Receptor
DNMT3A-IN-1
Cat.No: T63859
Synonym:
Target:
Fabomotizole hydrochloride
Cat.No: T4093
Synonym: Afobazole hydrochloride,CM346 hydrochloride
Target: MAO
Fabomotizole dihydrochloride
Cat.No: T70073
Synonym:
Target:
TargetMol Loading
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