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Cat. No. Product Name Target Signaling Pathways
T13782 MS432

MEK MAPK
MS432 is a highly selective PD0325901-based VHL-recruiting PROTAC degrader for MEK1 and MEK2.
T82378 Folate-MS432

PROTACs PROTAC
Folate-MS432作为PROTAC,通过叶酸受体依赖途径特异性降解癌细胞中的MEKs。
T17638 Boc-11-aminoundecanoic acid

Others; PROTAC Linker Others; PROTAC
Boc-11-aminoundecanoic acid 是一种属于 Alkyl/ether 类的 PROTAC linker,可用于 MS432 的合成。
T40233 (Iso)-MS4322

(Iso)-YS43-22,MS4322 (isomer),YS43-22 (isomer)

Histone Methyltransferase Chromatin/Epigenetic
(Iso)-MS4322 ((Iso)-YS43-22) 是一种具有选择性和强效性的蛋白质精氨酸甲基转移酶 5 (PRMT5) 降解剂,具有潜在的抗癌活性,有效地降低 MCF-7 细胞中的 PRMT5 蛋白水平,可抑制多种癌细胞的生长。
T17694 Br-C10-methyl ester

11-溴代十一烷酸甲酯

Others; PROTAC Linker Others; PROTAC
Br-C10-methyl ester 是一种属于 alkyl/ether 类的 PROTAC linker,可用于一系列 PROTAC 分子的合成。PROTAC 分子含有两个通过 linker 连接的不同配体,一种是 VHL 配体部分,另一种是靶蛋白配体。
T18668 (S,R,S)-AHPC-Me-C10-Br

Others Others
(S,R,S)-AHPC-Me-C10-Br is a chemically synthesized conjugate that functions as a ligand-linker for E3 ligases. This compound incorporates a VHL E3 ligase linker and MS432, derived from the MEK1/2 inhibitor PD0325901[1].
T18669 (S,R,S)-AHPC-Me-C10-NH2

Others Others
(S,R,S)-AHPC-Me-C10-NH2 is a chemical compound consisting of a synthesized E3 ligase ligand-linker conjugate that incorporates both a VHL ligand and a linker. This compound, (S,R,S)-AHPC-Me-C10-NH2, finds application in PROTAC MS432[1].

化合物

MS432
Cat.No: T13782
Synonym:
Target: MEK
Folate-MS432
Cat.No: T82378
Synonym:
Target: PROTACs
Boc-11-aminoundecanoic acid
Cat.No: T17638
Synonym:
Target: Others, PROTAC Linker
(Iso)-MS4322
Cat.No: T40233
Synonym: (Iso)-YS43-22,MS4322 (isomer),YS43-22 (isomer)
Target: Histone Methyltransferase
Br-C10-methyl ester
Cat.No: T17694
Synonym: 11-溴代十一烷酸甲酯
Target: Others, PROTAC Linker
(S,R,S)-AHPC-Me-C10-Br
Cat.No: T18668
Synonym:
Target: Others
(S,R,S)-AHPC-Me-C10-NH2
Cat.No: T18669
Synonym:
Target: Others
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