Cat. No. | Product Name | Target | Signaling Pathways |
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T12398 |
MP7
PDK1 抑制剂,PDK1 inhibitor |
PDK | PI3K/Akt/mTOR signaling |
MP7 (PDK1 inhibitor) 是磷酸肌醇依赖性激酶-1 (PDK1) 抑制剂。 | |||
T39941 |
MP-PEG4-Val-Lys-Gly-7-MAD-MDCPT
MP-PEG4-Val-Lys-Gly-7-MAD-MDCPT |
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MP-PEG4-Val-Lys-Gly-7-MAD-MDCPT is a Camptothecin-linker. MP-PEG4-Val-Lys-Gly-7-MAD-MDCPT is a drug-linker conjugate for antibody-drug conjugate (ADC). | |||
T81752 |
MP-PEG8-Val-Lys-Gly-7-MAD-MDCPT
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MP-PEG8-Val-Lys-Gly-7-MAD-MDCPT为喜树碱-接头化合物,属于抗体偶联活性分子(drug-linker conjugate for ADC)部分。该化合物在癌症及自身免疫性疾病研究中显示出研究潜力。 | |||
T38916 |
Antibacterial agent 51
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Antibacterial agent 51 (example 45) is a potent antibacterial compound effective against E. coli strains NCTC 13351, M 50, and 7 MP, with MIC values of 4, 8, and 8 mcg/mL, respectively (WO2013030733A1). | |||
T38917 |
Antibacterial agent 50
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Antibacterial agent 50 (example 47) is a compound that exhibits antibacterial activity. It shows minimum inhibitory concentration (MIC) values of 32, 64, and 128 mcg/mL against three strains of E. coli, namely NCTC 13351, M 50, and 7 MP, respectively (WO2013030733A1). | |||
T38915 | Antibacterial agent 32 | ||
Antibacterial agent 32 exhibits potent antimicrobial activity against E. coli strains NCTC 13351, M 50, and 7 MP, with minimum inhibitory concentration (MIC) values of 1 mcg/mL, 2 mcg/mL, and 8 mcg/mL, respectively (WO2013030733A1, example 43). | |||
T37522 | Teneligliptin | ||
Teneligliptin (MP-513) is a potent chemotype prolylthiazolidine-based DPP-4 inhibitor, which competitively inhibits human plasma, rat plasma, and human recombinant DPP-4 in vitro, with IC50s of approximately 1 nM. Teneligliptin (MP-513) inhibits all these DPP-4 enzymes in a concentration-dependent manner. The IC50s of Teneligliptin (MP-513) for rhDPP-4, human plasma, and rat plasma are 0.889, 1.75, and 1.35 nM, respectively. A study of enzyme inhibition kinetics is conducted for Teneligliptin (M... | |||
T36880 |
NHC-diphosphate
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NHC-diphosphate is an active phosphorylated intracellular metabolite of β-d-N4-Hydroxycytidine (NHC) as a diphosphate form[1]. NHC is a pyrimidine ribonucleoside and behaves as a potent anti-virus agent. NHC effectively inhibits the replication of venezuelan equine encephalitis virus (VEEV), Chikungunya virus (CHIKV) and hepatitis C virus (HCV)[1]. Huh-7 cells are incubated with (10-50 μM; 4 h) NHC or a McGuigan phosphoramidate prodrug of NHC.Intracellular levels of the parental compounds and ... | |||
T36881 | NHC-diphosphate triammonium | ||
NHC-triphosphate triammonium is an active phosphorylated intracellular metabolite of β-d-N4-Hydroxycytidine (NHC) as a triphosphate form[1]. NHC-triphosphate triammonium is a weak alternative substrate for the viral polymerase and can be incorporated into HCV replicon RNA[1][2]. In an intracellular metabolism assay, HCV replicon cells are treated with 10 μM 3H-labeled NHC, and intracellular nucleotide levels are determined after 1, 2 and 8 hours incubations. NHC is rapidly convered into the mono... |