Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T2625 |
MK-0752
|
Beta Amyloid; Gamma-secretase | Neuroscience; Proteases/Proteasome; Stem Cells |
MK0752 是一种高效的、特异性的、可穿过血脑屏障的、口服活性的 γ-分泌酶(γ-secretase)抑制剂,对人 SH-SY5Y 细胞 Aβ40 呈剂量依赖性降低(IC50=5 nM)。它能够降低体内新生的中枢神经系统 Aβ。 | |||
T2625L |
MK-0752 Sodium
MK 0752,MK0752,MK-0752 |
||
Sodium MK-0752 is a novel and potent gamma-secretase inhibitor that has been evaluated in clinical trials for the treatment of various types of cancer. |