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抑制剂 & 化合物

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Cat. No.	Product Name	Target	Signaling Pathways
T1097	Loratadine 氯雷他定,SCH 29851,Loratidine	Influenza Virus; Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Microbiology/Virology; Neuroscience
	Loratadine (SCH 29851) 是一种组胺 H1受体反向激动剂，IC50>32 μM。它抑制炎症介质的免疫释放，具有抗登革热病毒的活性。
T70306	Loratadine N-oxide
	Loratadine N-oxide is a metabolite of the histamine H1 receptor inverse agonist loratadine.
T20814	Loratadine specified impurity F 11-Fluoro dihydroloratadine
	Loratadine specified impurity F is a fluorinated analog of Loratadine.
T20815	4-Chloroloratadine 4-Chloro loratadine,Loratadine specified impurity C
	4-Chloroloratadine is an impurity of Loratadine, a nonsedating-type histamine H1-receptor.
T20816	Isoloratadine Iso loratadine,Loratadine specified impurity E
	Isoloratadine is a Loratadine impurity. It is an isomer of Loratadine used for the preparation of ureas and tricyclic amides, it is also useful for inhibition of G-protein function and treatment of proliferative diseases.
T70305	Zoledronate trisodium hydrate
	Zoledronate trisodium is a Bone Resorption Inhibitor and Osteoporosis Therapy Adjunct
T65952	N-Methyl Desloratadine
	N-Methyl Desloratadine 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T65952，CAS号为 38092-89-6。
T36618	Rupatadine
	Rupatadine (UR-12592) is a potent dual PAF/H1 antagonist with Ki of 0.55/0.1 uM(rabbit platelet membranes/guinea pig cerebellum membranes).IC50 value:Target: PAF/H1 antagonistin vitro: Rupatadine competitively inhibited histamine-induced guinea pig ileum contraction (pA2 = 9.29 +/- 0.06) without affecting contraction induced by ACh, serotonin or leukotriene D4 (LTD4). It also competitively inhibited PAF-induced platelet aggregation in washed rabbit platelets (WRP) (pA2 = 6.68 +/- 0.08) and in hu...

化合物

Loratadine

Cat.No: T1097

Synonym: 氯雷他定,SCH 29851,Loratidine

Target: Influenza Virus, Histamine Receptor

Loratadine specified impurity F

Cat.No: T20814

Synonym: 11-Fluoro dihydroloratadine

Target:

4-Chloroloratadine

Cat.No: T20815

Synonym: 4-Chloro loratadine,Loratadine specified impurity C

Target:

Isoloratadine

Cat.No: T20816

Synonym: Iso loratadine,Loratadine specified impurity E

Target:

Zoledronate trisodium hydrate

Cat.No: T70305

Synonym:

Target:

N-Methyl Desloratadine

Cat. No.	Product Name	Target	Signaling Pathways
T2520	Desloratadine Sch34117,地氯雷他定,NSC 675447	Endogenous Metabolite; Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Metabolism; Neuroscience
	Desloratadine (Sch34117) 是非镇静H1抗组胺药 Loratadine 的主要口服代谢物，可减少对支气管平滑肌、毛细血管和胃肠道平滑肌中 H1 受体的典型组胺能作用，包括血管舒张、支气管收缩、血管通透性增加、疼痛、瘙痒和胃肠道平滑肌的痉挛性收缩。它是一种选择性H1受体拮抗剂，具有抗过敏和抗炎活性。