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Search Results for " linezolid "

14

抑制剂 & 化合物

1

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T0391	Linezolid PNU-100766,雷奈佐利	MAO; Antibacterial; Antibiotic	Metabolism; Microbiology/Virology; Neuroscience
	Linezolid (PNU-100766) 是恶唑烷酮类合成抗生素，抑制细菌蛋白质合成的起始阶段，具有抗感染作用。
T11853	Linezolid-d3 Linezolid D3,PNU-100766 D3	Others	Others
	Linezolid D3, a deuterium-labeled version of Linezolid, is a synthetic antibiotic designed to halt the initiation of bacterial protein synthesis.
T39154	Demethyl linezolid
	Demethyl linezolid is an impurity observed in linezolid, an antimicrobial compound. It exhibits effective antimicrobial properties against various human and veterinary pathogens.
T12627	(R)-Linezolid (R)-PNU-100766	Others	Others
	(R)-Linezolid is an impurity of Linezolid . Linezolid acts by inhibiting the initiation of bacterial protein synthesis.
T19645	PNU-100440 (5R)-3-[3-氟-4-(4-吗啡啉基)苯基]-5-羟甲基-2-恶唑烷酮	Others	Others
	PNU-100440 是一种生物活性化合物。它是合成利奈唑胺二聚物的中间体，利奈唑胺二聚物是抗菌剂利奈唑胺的杂质。
T4165	Delpazolid LCB01-0371	Antibacterial; Antibiotic	Microbiology/Virology
	Delpazolid (LCB01-0371) 是一种恶唑烷酮类新型抗生素，能抑制MSSA 和MRSA 的生长，对它们的MIC90值都为 2 μg/mL。
T16718	Radezolid RX-1741,雷得唑来	Antibacterial; Antibiotic	Microbiology/Virology
	Radezolid (RX-1741) 是一种噁唑烷酮类抗生素。它对衣原体，军团菌葡萄球菌，和Linezolid 耐药菌株有活性。
T37841	PNU 142300
	PNU 142300 is an inactive metabolite of the oxazolidinone antibiotic linezolid .
T37465	CAY10742
	CAY10742 is an orally bioavailable oxadiazole antibiotic.1It is active against the Gram-positive bacteriaS. aureus,S. epidermidis,S. haemolyticus,B. cereus,B. licheniformis,E. faecalis, andE. faecium(MICs = 1-4 μg/ml), including laboratory strains and clinical isolates with varying degrees of resistance to methicillin, vancomycin, linezolid, and other antibiotics. CAY10742 (40 mg/kg) reduces the number of bacteria in mouse neutropenic thigh models of linezolid-sensitive or -resistant methicillin...
T69176	YycG inhibitor 16
	YycG inhibitor 16 is a novel YycG inhibitor, inhibiting planktonic cells of E. faecalis, including the vancomycin- or linezolid-resistant strains.
T23947	DA-7867 UNII-491MT9GU8K,DA 7867,DA7867
	DA-7867 is a novel oxazolidinone. DA-7867 had the lowest MIC for 90% of the aerobic gram-positive bacterial strains tested (≤0.25 μg/ml) and it was more potent than linezolid. DA-7867 was the most active drug with a MIC(90) of 0.125 μg/ml.
T27964	Voxvoganan LTX109,Lytixar,LTX-109,LTX 109
	Lytixar is a Synthetic Antimicrobial Peptide, it shows activity against Daptomycin-Nonsusceptible, Methicillin-Resistant, Vancomycin-Intermediate, Vancomycin-Resistant, and Linezolid-Nonsusceptible Staphylococcus aureus. LTX-109 demonstrated a MIC range o
T76990	Suvratoxumab
	Suvratoxumab (MEDI4893) 是一种长效且具有亲和力高的人源化抗 α-毒素单克隆抗体(IgG1κ 型)。Suvratoxumab 能有效中和 α-毒素 (一种关键的金黄色葡萄球菌毒力因子)。Suvratoxumab 可提高免疫功能低下的小鼠肺炎模型的存活率并减少肺损伤。Suvratoxumab 还可增强Vancomycin 或Linezolid 的抗菌活性。
T23451	Tedizolid HCl (856866-72-3 free base) Tedizolid HCl	Others	Others
	Tedizolid HCl is a reversible, novel oxazolidinone antibiotic (IC50: for MAO-A (monoamine oxidase-A), 8.7 uM; for MAO-B, 5.7 uM). It is the first oxazolidinone to be approved since linezolid in 2000. Tedizolid phosphate is the second commercially availabl

化合物

Cat.No: T0391

Synonym: PNU-100766,雷奈佐利

Target: MAO, Antibacterial, Antibiotic

Cat.No: T11853

Synonym: Linezolid D3,PNU-100766 D3

Target: Others

Demethyl linezolid

Cat.No: T39154

(R)-Linezolid

Cat.No: T12627

Synonym: (R)-PNU-100766

Target: Others

Cat.No: T19645

Synonym: (5R)-3-[3-氟-4-(4-吗啡啉基)苯基]-5-羟甲基-2-恶唑烷酮

Target: Others

Cat.No: T4165

Synonym: LCB01-0371

Target: Antibacterial, Antibiotic

Cat.No: T16718

Synonym: RX-1741,雷得唑来

Target: Antibacterial, Antibiotic

Cat.No: T37841

Cat.No: T37465

YycG inhibitor 16

Cat.No: T69176

Cat.No: T23947

Synonym: UNII-491MT9GU8K,DA 7867,DA7867

Cat.No: T27964

Synonym: LTX109,Lytixar,LTX-109,LTX 109

Cat.No: T76990

Tedizolid HCl (856866-72-3 free base)

Cat.No: T23451

Synonym: Tedizolid HCl

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
TN6603	(S)-N-Glycidylphthalimide (S)-N-缩水甘油邻苯二甲酰亚胺,2-[(2S)-2-Oxiranylmethyl]-1H-isoindole-1,3(2H)-dione	Others	Others
	(S)-N-Glycidylphthalimide (2-[(2S)-2-Oxiranylmethyl]-1H-isoindole-1,3(2H)-dione) 是一种邻苯二甲酰亚胺衍生物，用作制备抗生素利奈唑胺的中间体。

天然产物

(S)-N-Glycidylphthalimide

Cat.No: TN6603

Synonym: (S)-N-缩水甘油邻苯二甲酰亚胺,2-[(2S)-2-Oxiranylmethyl]-1H-isoindole-1,3(2H)-dione

Target: Others

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