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抑制剂 & 化合物

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天然产物

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Cat. No. Product Name Target Signaling Pathways
T19783 Dehydroabiethylamine

NSC-2955,NSC 2955,Dehydroabietylamine,NSC2955,Leelamine free base,Leelamine,脱氢松香胺

P450; PDK Metabolism; PI3K/Akt/mTOR signaling
Dehydroabiethylamine (NSC-2955) 是肝脏 CYP2B 活性的诱导剂。 Dehydroabiethylamine 抑制丙酮酸脱氢酶激酶 (PDK) 和细胞内胆固醇转运,具有抗肿瘤活性。

化合物

Dehydroabiethylamine
Cat.No: T19783
Synonym: NSC-2955,NSC 2955,Dehydroabietylamine,NSC2955,Leelamine free base,Leelamine,脱氢松香胺
Target: P450, PDK
Cat. No. Product Name Target Signaling Pathways
T11834 Leelamine hydrochloride

Others Others
Leelamine hydrochloride, a tricyclic diterpene extracted from pine tree bark, inhibits the transcriptional activity of the androgen receptor, known to regulate fatty acid synthesis [2,3]. This compound acts as a cannabinoid receptor type 1 (CB1) agonist and suppresses SREBP1-regulated fatty acid/lipid synthesis in prostate cancer cells, irrespective of androgen receptor status.

天然产物

Leelamine hydrochloride
Cat.No: T11834
Synonym:
Target: Others
TargetMol Loading
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