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Cat. No.	Product Name	Target	Signaling Pathways
T15818	LY367385	FXR	Metabolism
	LY367385 is a highly effective and selective mGluR1a antagonist. LY367385 has neuroprotective, anticonvulsant, and antiepileptic effects. Compared with > 100 μM for mGlu5a, LY367385 has an IC50 of 8.8 μM for inhibits of quisqualate-induced phosphoinositide (PI) hydrolysis.
T39406	(±)-LY367385 (±)-LY367385
	(±)-LY367385 is the racemic form of LY367385, and LY367385 is a highly potent and selective mGluR1a antagonist. LY367385 exhibits a high inhibitory activity against quisqualate-induced phosphoinositide (PI) hydrolysis, with an IC50 value of 8.8 μM. In contrast, its inhibitory activity against mGlu5a is greater than 100 μM.
T60355	LY367385 hydrochloride
	LY367385 hydrochloride 是一种高效且选择性的mGluR1a 拮抗剂，抑制喹喹啉诱导的磷酸肌醇水解的IC50值为 8.8 μM，而对 mGlu5a 的IC50值大于 100 μM。LY367385 hydrochloride 具有神经保护，抗惊厥和抗癫痫作用。