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Cat. No. Product Name Target Signaling Pathways
T63140 LSD1-IN-20

Histone Demethylase Chromatin/Epigenetic
LSD1-IN-20 是一种有效的 LSD1/G9a 双重抑制剂,其 Ki 值分别为 0.44 和 0.68 μM。LSD1-IN-20 在体外实验中对 THP-1 白血病细胞和 MDA-MB-231 乳腺癌细胞显示出抗增殖活性,72 h 时 IC50 分别为 0.511.60 μM。
T36668 Geranylgeranoic Acid

Geranylgeranoic acid (GGA) is an isoprenoid that has been found inS. chinensisand has anticancer activity.1It induces apoptosis in Huh7 and PLC/PRF/5 human hepatoma cells and MLE-10 transformed mouse hepatocytes, but not primary mouse hepatocytes, when used at concentrations ranging from 1 to 20 μM. GGA (10 μM) induces apoptosis in Huh7 cellsvialoss of the mitochondrial membrane potential and activation of interleukin-1β-converting enzyme (ICE) and cysteine protease precursor 32 (CPP32).2It also...

化合物

LSD1-IN-20
Cat.No: T63140
Synonym:
Target: Histone Demethylase
Geranylgeranoic Acid
Cat.No: T36668
Synonym:
Target:
TargetMol Loading
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