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Cat. No.	Product Name	Target	Signaling Pathways
T10352	APTO-253 LOR-253,LT-253	Apoptosis; c-Myc; KLF	Apoptosis; Cell Cycle/Checkpoint; MAPK
	APTO-253 (LOR-253) 抑制 c-Myc 表达，稳定 G-四链体 DNA，并诱导急性髓细胞白血病细胞的细胞周期停滞和凋亡。它通过诱导 KLF4 肿瘤抑制因子介导抗癌活性，具有抗关节炎活性。
T71948	Flufenacet
	Flufenacet is a herbicide, inhibiting very-long-chain fatty acid elongase (VLCFAE) synthesis.
T70272	L-162782
	L-162782 is a nonpeptide agonist of angiotensin AT1 receptor.
T70706	APTO-253 isomer
	APTO-253 isomer is an isomer of APTO-253 with the Fluoro-atom in 6-position. APTO-253 also known as LOR-253, LT-253, is a small molecule inhibitor of human metal-regulatory transcription factor 1 (MTF-1) with potential antitumor activity. MTF-1 inhibitor LOR-253 inhibits MTF-1 activity and thereby induces the expression of MTF-1 dependent tumor suppressor factor Kruppel like factor 4 (KLF4). This subsequently leads to the downregulation of cyclin D1, blocking cell cycle progression and prolifer...
T70273	APTO-253 HCl
	APTO-253, also known as LOR-253, LT-253, is a small molecule inhibitor of human metal-regulatory transcription factor 1 (MTF-1) with potential antitumor activity. MTF-1 inhibitor LOR-253 inhibits MTF-1 activity and thereby induces the expression of MTF-1 dependent tumor suppressor factor Kruppel like factor 4 (KLF4). This subsequently leads to the downregulation of cyclin D1, blocking cell cycle progression and proliferation. This agent also causes decreased expression of genes involved in tumor...