Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-01251 |
DUSP26 Protein, Human, Recombinant (His & SUMO)
MKP-8,NATA1,DSP-4,SKRP3,DUSP26,MKP8,LDP- |
Human | E. coli |
Inactivates MAPK1 and MAPK3 which leads to dephosphorylation of heat shock factor protein 4 and a reduction in its DNA-binding activity. Inhibits MAP kinase p38 by dephosphorylating it and inhibits p38-mediated apoptosis in anaplastic thyroid cancer cells. Can also induce activation of MAP kinase p38 and c-Jun N-terminal kinase (JNK). |