首页工具

登录

搜索结果

Search Results for " l6 cells "

4

抑制剂 & 化合物

3

天然产物

如果没找到您满意的产品或者您对产品有其他要求，可以联系我们专业顾问为您提供针对性的合理建议。 QQ咨询网站留言咨询

Cat. No.	Product Name	Target	Signaling Pathways
T79557	fac-[Re(CO)3(L6)(H2O)][NO3]	Apoptosis	Apoptosis
	fac-[Re(CO)3(L6)(H2O)][NO3]（compound 6）是一种具有针对线粒体功能失调的抗癌活性的铼(I)三羰基水配合物。该化合物对前列腺癌细胞展现出显著的细胞毒性，具有50 nM的IC50值（PC-3细胞）。fac-[Re(CO)3(L6)(H2O)][NO3]能够主要集中在细胞核，抑制PC3细胞的ATP生成并诱导细胞凋亡，而不触发坏死、焦亡或自噬过程。
T35636	SHS4121705
	SHS4121705 is an orally bioavailable mitochondrial uncoupler.1It increases oxygen consumption rate in L6 rat myoblast cells with an EC50value of 4.3 μM. SHS4121705 (25 mg/kg per day in the diet) reduces hepatic steatosis, liver triglyceride levels, and plasma alanine aminotransferase (ALT) levels in Stelic animal model (STAM) mice, a model of non-alcoholic steatohepatitis (NASH). 1.Salamoun, J.M., Garcia, C.J., Hargett, S.R., et al.6-Amino[1,2,5]oxadiazolo[3,4-b]pyrazin-5-ol derivatives as effic...
T36555	Tyr-α-CGRP (human) (trifluoroacetate salt)
	Tyr-α-CGRP is an N-terminal extended tyrosinated analogue of α-calcitonin gene-related peptide . It binds to amylin receptors AMY1 and AMY3 in COS-7 cells expressing the human receptors (IC50s = 141 and 1.86 nM, respectively). Tyr-α-CGRP also binds to and stimulates cAMP accumulation in rat L6 myocytes (IC50 = 4 nM; EC50 = 12 nM). It also binds to rat brain and spleen membrane preparations (IC50s = 0.2 and 0.5 nM, respectively), induces positive chronotropic and inotropic effects in isolated rig...
T35813	CAY10592
	Peroxisome proliferator-activated receptors (PPARs) α, δ, γ are ligand-activated nuclear transcription factors involved in the regulation of energy homeostasis as well as insulin sensitivity and glucose metabolism. Pharmacologies of PPARδ receptor agonists, though relatively obscure, have recently been reported to elevate high-density lipoprotein (HDL) cholesterol and lower plasma triglyceride (TG) levels in obese insulin resistant rhesus monkeys. CAY10592 is a full PPARδ agonist (EC50 = 30 nM) ...

化合物

fac-[Re(CO)3(L6)(H2O)][NO3]

Cat.No: T79557

Target: Apoptosis

Cat.No: T35636

Tyr-α-CGRP (human) (trifluoroacetate salt)

Cat.No: T36555

Cat.No: T35813

Cat. No.	Product Name	Target	Signaling Pathways
T8242	Sabinene	Others	Others
	Sabinene 是香料添加剂，具有成为下一代飞机燃料成分的成分。
T5690	7,4'-Di-O-methylapigenin 芹菜素二甲醚,4',7-DIMETHOXY-5-HYDROXYFLAVONE	Amylase	Metabolism
	7,4'-Di-O-methylapigenin (4',7-DIMETHOXY-5-HYDROXYFLAVONE) 可能具有抗真菌c.zeyheri 的作用，是一种潜在的抗真菌药物。它还能抑制药物流出泵(IC50 = 51.64μg /毫升)。
T74199	Beauverolide Ka
	Beauverolide Ka 是一种环四缩酚肽，是 Beauveria bassiana 真菌的代谢产物。Beauverolide Ka 浓度为 50 μM 时可刺激培养的大鼠 L6 成肌细胞的葡萄糖摄取。Beauverolide Ka 在 10 μM 时表现出对 HEI-OC1 细胞的保护作用，并且在 L6 成肌细胞和肌管中表现出剂量依赖性活性。

天然产物

Cat.No: T8242

Target: Others

7,4'-Di-O-methylapigenin

Cat.No: T5690

Synonym: 芹菜素二甲醚,4',7-DIMETHOXY-5-HYDROXYFLAVONE

Target: Amylase

Beauverolide Ka

Cat.No: T74199

我们的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。

Copyright © 2015-2024 TargetMol Chemicals Inc. All rights reserved. 沪ICP备20019793号-4

沪公网安备 31010602006700号

沪公网安备 31010602006700号

TargetMol Loading

联系我们

电话：

400-820-0310

邮箱：

service@tsbiochem.com

QQ：

2881945090（终端用户）

2885109491（经销商）

经销：

终端：

地址：

上海市静安区江场三路238号8楼