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Cat. No.	Product Name	Target	Signaling Pathways
T3182	L-778123 hydrochloride L 778123	Telomerase; Transferase	DNA Damage/DNA Repair; Metabolism
	L-778123 hydrochloride 是一种FPTase 和GGPTase-I 双重抑制剂，IC50分别为2 nM 和 98 nM。
T3182L	L-778123 free base L-778,123,L 778123,L-778123,L778123,L 778,123
	L-778123 is an inhibitor of FPTase and GGPTase-I. The combination of L-778123 and radiotherapy at dose level 1 showed acceptable toxicity in patients with locally advanced pancreatic cancer.
T70133	BAY-846
	BAY-846 is an allosteric MEK inhibitor with long half-lives, high bioavailabilities, low brain penetration potential and high efficacy in a K-Ras-mutated A549 xenograft model.
T70134	L-778123 Dihydrochloride
	L-778123 is an inhibitor of FPTase and GGPTase-I, which was developed in part because it can completely inhibit Ki-Ras prenylation. The combination of L-778,123 and radiotherapy at dose level 1 showed acceptable toxicity in patients with locally advanced pancreatic cancer. Radiosensitization of a patient-derived pancreatic cancer cell line was observed.