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Cat. No. Product Name Target Signaling Pathways
T13320L VU591

Potassium Channel Membrane transporter/Ion channel
VU591 是选择性的肾外髓钾通道抑制剂,IC50为 0.24 μM。
T13320 VU591 hydrochloride

Potassium Channel Membrane transporter/Ion channel
VU591 hydrochloride 是选择性的肾外髓钾通道抑制剂,IC50为 0.24 μM。
T23516 VU590

Potassium Channel Membrane transporter/Ion channel
VU590 是一种具有高效性和中等选择性的肾外髓质钾 ROMK (Kir1.1) 抑制剂。VU590 抑制 Kir7.1,可调节子宫肌层收缩力和黑皮质素信号传导。
T6592 ML133 hydrochloride

ML133 HCl,(4-甲氧基苄基)(1-萘基甲基)胺盐酸盐

Potassium Channel Membrane transporter/Ion channel
ML133 hydrochloride (ML133 HCl) 是选择性的Kir2家族通道抑制剂,在pH 7.4 和pH 8.5 时的IC50值分别为1.8 μM 和290 nM。
TP2113 Tertiapin LQ

Blocker of Kir1.1 channels; displays >250-fold selectivity for Kir1.1 (Kd values are 1.1, 274 and 361 nM for Kir1.1, Kir3.1/3.2 and Kir3.1/3.4 respectively). Derivative of tertiapin-Q.
T17240 VU041

Others Others
VU041 is an inhibitor of Anopheles gambiae and Aedes aegypti inward rectifier potassium 1 channels (IC50: 2.5 μM and 1.7 μM, respectively). VU041 inhibits appreciably is mammalian Kir2.1 (IC50: 12.7 μM) and has less inhibitory effect on mammalian Kir1.1, Kir4.1, Kir6.2/SUR1, and Kir7.1.
TP2114 Tertiapin-Q

A high affinity blocker for inward-rectifier K+ channels, this compound is a stable derivative of the bee venom toxin tertiapin. Binds to ROMK1 (Kir1.1) and GIRK1/4 (Kir3.1/3.4) channels with high affinity (Ki values are 1.3 and 13.3 nM respectively) and
T83749 Tertiapin LQ TFA

TPNLQ

Tertiapin LQ是源自蜜蜂毒素肽tertiapin的肽衍生物,同时也是向内整流钾(Kir)通道的抑制剂。它能够抑制由G蛋白激活的向内整流钾通道1(GIRK1)和GIRK4(即Kir3.1Kir3.4)组成的异源多聚钾通道,以及向内整流钾通道1Kir1.1)。在活体内,tertiapin LQ抑制在雪貂中对条件刺激的Purkinje细胞暂停响应。

化合物

VU591
Cat.No: T13320L
Synonym:
Target: Potassium Channel
VU591 hydrochloride
Cat.No: T13320
Synonym:
Target: Potassium Channel
VU590
Cat.No: T23516
Synonym:
Target: Potassium Channel
ML133 hydrochloride
Cat.No: T6592
Synonym: ML133 HCl,(4-甲氧基苄基)(1-萘基甲基)胺盐酸盐
Target: Potassium Channel
Tertiapin LQ
Cat.No: TP2113
Synonym:
Target:
VU041
Cat.No: T17240
Synonym:
Target: Others
Tertiapin-Q
Cat.No: TP2114
Synonym:
Target:
Tertiapin LQ TFA
Cat.No: T83749
Synonym: TPNLQ
Target:
TargetMol Loading
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