Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T22879 |
JNJ 10191584 maleate
JNJ 10191584 maleate salt,VUF6002 maleate |
Histamine Receptor | GPCR/G Protein; Immunology/Inflammation; Neuroscience |
JNJ 10191584 maleate (VUF6002 maleate) 是一种具有口服活性的选择性 H4 受体拮抗剂 (Ki = 26 nM)。 JNJ 10191584 maleate 抑制嗜酸性粒细胞和肥大细胞的趋化性(IC50 = 530 nM 和 138 nM)。 | |||
T27658 |
JNJ-10191584
VUF-6002,JNJ10191584 |
||
JNJ-10191584, a potent and selective antagonist at the histamine H4 receptor, has antiinflammatory and analgesic effects in animal studies of acute inflammation. |