1
7
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T76972 |
Tozorakimab
|
||
Tozorakimab (MEDI-3506) 是一种靶向白介素-33 (interleukin-33) 的人免疫球蛋白 G1 单克隆抗体。Tozorakimab 可用于研究慢性阻塞性肺疾病。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-02789 |
IL-33 Protein, Canine, Recombinant
白介素,interleukin 33,白细胞介素 |
Canine | E. coli |
IL-33 Protein, Canine, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.8 kDa and the accession number is O97863. | |||
TMPY-05449 |
IL-33 Protein, Cynomolgus, Recombinant
白细胞介素,interleukin 33,白介素 |
Cynomolgus | E. coli |
IL-33 Protein, Cynomolgus, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 18.1 kDa and the accession number is A0A2K5W3I1. | |||
TMPJ-01210 |
IL-33 Protein, Mouse, Recombinant
Interleukin-1 family member 11,白细胞介素,NF-HEV and IL-... |
Mouse | E. coli |
Mouse Interleukin 33 (IL-33) is a 30 kDa proinflammatory cytokine which may also regulates gene transcription in producer cells. IL-33 is constitutively expressed in smooth muscle and airway epithelia. IL-33 was identified based on sequence and structural homology with IL-1 family cytokines. It is up‑regulated in arterial smooth muscle, dermal fibroblasts, and keratinocytes following IL-1 alpha or IL‑1 beta stimulation. IL-33 is structurally related to IL-1, which induces helper T cells to produ... | |||
TMPY-00861 |
IL-33 Protein, Human, Recombinant
IL1F11,C9orf26,NFEHEV,NF-HEV,DVS27,白介素,interleukin ... |
Human | E. coli |
IL-33 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 18 kDa and the accession number is O95760-1. | |||
TMPJ-00617 |
IL-33 Protein, Rhesus macaque, Recombinant (His)
Interleukin-33,IL1F11,IL33,白介素,白细... |
Rhesus | E. coli |
Interleukin-33 (IL-33) belongs to the IL-1 superfamily. IL33 is highly expressed in endothelial venules found in tonsils, Peyer patches and mesenteric lymph nodes, but almost undetectable in placenta. IL33 induces the production of T helper-2 (Th2)-associated cytokines. IL-33 is a cytokine that mediates its biological effects by binding to and signals through IL1RL1/ST2 and IL-1 Receptor Accessory Protein (IL1RAP), activating intracellular molecules in the NF-κB and MAP kinase signaling pathways... | |||
TMPK-00163 |
IL-33 Protein, Cynomolgus, Recombinant (His)
IL1F11,C9orf26 Z,C9ORF26,DV27,RP11-575C20.2,NFEHEV,IL33<... |
Cynomolgus | HEK293 Cells |
Interleukin-33 (IL-33) is a cytokine belonging to the IL-1 family, playing a role in inflammatory, infectious and autoimmune diseases and expressed in the cellular nucleus in several tissues. High levels of IL-33 are expressed in epithelial barrier tissues and endothelial barriers. ST2 is a receptor for IL-33, expressed selectively on a subset of Th2 cells, mediating some of their functions. | |||
TMPK-01029 |
IL-1RAP/IL-1RAcP Protein, Mouse, Recombinant (aa 21-367, His)
C3orf13,IL1RAP,IL-1 R3,IL-1 RAcP |
Mouse | HEK293 Cells |
Interleukin (IL)-1R3 is the co-receptor in three signaling pathways that involve six cytokines of the IL-1 family (IL-1α, IL-1β, IL-33, IL-36α, IL-36β and IL-36γ). In many diseases, multiple cytokines contribute to disease pathogenesis. For example, in asthma, both IL-33 and IL-1 are of major importance, as are IL-36 and IL-1 in psoriasis. |