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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T38423 |
CL097
CL097 |
Reactive Oxygen Species; TLR | Immunology/Inflammation; Metabolism; NF-κB |
CL097 是 TLR7 和 TLR8 的有效激动剂。 CL097 诱导巨噬细胞中的促炎细胞因子和 NADPH 氧化酶引发,从而增加 fMLF 刺激的 ROS 产生。 | |||
T7710 |
MOFEBUTAZONE
|
Others | Others |
Mofebutazone 抑制前列腺素和白三烯的免疫释放。 | |||
T19675 |
SM360320
CL-087,SM 360320,CL 087,1V136,SM-360320,CL087 |
TLR | Immunology/Inflammation |
SM360320 (CL-087) 是一种有效的特异性 TLR7 激动剂。 SM360320 除了其 IFN 介导的活性外,还通过 I 型 IFN 非依赖性机制抑制肝细胞中的 HCV 复制。 SM360320 可用于研究作为治疗性 DNA 疫苗的免疫佐剂。 | |||
T36503 |
Sodium Hydrogen Sulfide (hydrate)
|
Others | Others |
Sodium Hydrogen Sulfide (hydrate) 与一氧化氮一样,是一种重要的气体介质,对哺乳动物的免疫、神经、心血管和肺系统有重要影响。Sodium Hydrogen Sulfide (hydrate)是一种H2S 供体,常用于细胞和整个动物实验系统。例如,它被用来证明H2S 促进中性粒细胞迁移,减少气道炎症,保护神经轴突、心脏和肠道免受化学或缺血再灌注损伤。 | |||
T81043 |
Tapderimotide
hTERT (691–705) |
||
Tapderimotide(hTERT (691–705))为主动免疫疗法中使用的免疫药剂。 | |||
T82951 |
a-TGF (34-43), rat
|
||
a-TGF (34-43), rat 是一种用于免疫研究的活性肽。 | |||
T33733 |
N-Retinoylleucine
|
||
N-Retinoylleucine has less toxicity and has similar immunological effects as retinoic acid. | |||
T13912 |
Tacalcitol
1,24(R)-Dihydroxyvitamin D3,他卡西醇,1.alpha.,24R-Dihydroxyvitamin D3 |
Others | Others |
Tacalcitol (1,24(R)-Dihydroxyvitamin D3; 1.alpha.,24R-Dihydroxyvitamin D3) promotes normal bone development by regulating calcium. Tacalcitol modulates immunological and inflammatory processes. | |||
T81274 |
Riletamotide
hTERT (651-665) |
||
Riletamotide作为一种免疫剂,用途在于主动免疫。 | |||
T81607 |
Omramotide
|
||
Omramotide是一种免疫制剂,用途为主动免疫(抗肿瘤)。 | |||
T81076 |
Sucantomotide
|
||
Sucantomotide是用于激活免疫(抗肿瘤)的免疫制剂。 | |||
T81588 |
Oximbomotide
|
||
Oximmotide为用于主动免疫(抗肿瘤)的药剂。 | |||
T82473 |
Enavermotide
UCP2 |
||
Enavermotide (UCP2)是用于主动免疫(抗肿瘤)的免疫制剂。 | |||
T80853 |
Vorumotide
|
||
Vorumotide是一种具有主动免疫功能的免疫增强剂,同时也用作抗肿瘤药物。 | |||
T82435 |
Etimumotide
|
||
Etimumotide作为一种主动免疫的免疫剂和抗肿瘤剂,显示出其在生物医学领域的双重功能。 | |||
T81858 |
Marlumotide
|
||
Marlumotide是一种免疫调节剂,具有主动免疫和抗癌作用。 | |||
T82624 |
D-{Ala-Ala-Ala-Ala-Ala}
|
||
D-{Ala-Ala-Ala-Ala-Ala}为五肽化合物,作为免疫反应抑制剂使用。 | |||
T81252 |
RTQLLWTPAAPTAMA TFA
|
||
RTQLLWTPAAPTAMA TFA为肽类抗原,用于免疫应答中的药物传递。 | |||
T83141 |
Alnuctamab
EM901,CC-93269 |
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Alnuctamab (EM901)为一种不对称双臂人源化IgG T细胞接合器,主要应用于免疫学研究。 | |||
T76560 |
Imsamotide
|
||
Imsamotide (IDO194-214) 为一种具有序列 DTLLKALLEIASCLEKALQVF 的吲哚胺 2,3-双加氧酶 (IDO) 肽。它同时作为主动免疫的免疫剂和抗肿瘤剂。 | |||
T74726 | CL845 | ||
CL845 是 STING 激动剂 CL656 的类似物。CL845 可用于合成靶向 STING(干扰素基因刺激物)的可结合 PRR 配体。CL845 可用于癌症、免疫系统疾病或感染的研究。 | |||
T37045 |
1,3,4,6-Tetra-O-acetyl-2-azido-2-deoxy-α-D-Mannopyranose
|
||
1,3,4,6-Tetra-O-acetyl-2-azido-2-deoxy-α-D-mannopyranose is an analog of N-acetylmannosamine (ManNAc) and a building block.1,2It has been used as a precursor in the synthesis of differently substituted trimers of the group AN. meningitidiscapsular polysaccharide repeating unit for use in immunological experiments.2It has also been used in the synthesis of fluorescent probes for lysosomal labeling.3 | |||
T77106 | Odulimomab | ||
Odulimomab (anti-LFA1) 是一种抗 LFA-1单克隆抗体。Odulimomab 抑制 T 淋巴细胞增殖,对缺血再灌注损伤有保护作用。Odulimomab 可用于移植排斥反应和免疫疾病的研究。 | |||
T81328 |
Quazomotide
|
||
Quazomotide为WT1 II类肽表位,具有RSDELVRHHNMHQRNMTKL序列。该化合物通过特异性激活CD4(+)反应,以识别并攻击WT1(+)肿瘤细胞。同时,Quazomotide作为一种主动免疫治疗剂,用于抗肿瘤疗法。 | |||
T78178 |
PI5P4Kα-IN-1
|
Others | Others |
PI5P4Kα-IN-1(化合物13)是一种针对PI5P4Kα和PI5P4Kβ具有选择性抑制作用的化合物(IC50分别为2 μM和9.4 μM)。它适用于癌症、代谢和免疫紊乱相关研究。 | |||
T79821 |
DGKα-IN-2
|
||
DGKα-IN-2(例48)是一种具有IC50为0.9 nM的DGKα抑制剂。该化合物能显著增强T细胞增殖与功能,从而提升抗PD-1治疗的抗肿瘤效果,对肿瘤与免疫学领域的研究具有潜在价值。 | |||
T74718 |
STING modulator-5
|
||
STINGmodulator-5(compound 38)为THP-1和外周血单个核细胞(PBMC)的拮抗剂,其在THP-1上的pIC50值为8.9,在PBMC上的pIC50值为8.1。此化合物适用于免疫性疾病研究。 | |||
T79812 |
BTK-IN-27
|
BTK | Angiogenesis; Tyrosine Kinase/Adaptors |
BTK-IN-27(示例8)作为一种BTK抑制剂,具有高效的IC50值为0.2 nM。在TMD8细胞中,该化合物展现出显著的抗增殖能力,IC50值低于5 nM。BTK-IN-27适用于癌症、淋巴瘤、白血病及免疫性疾病研究领域。 | |||
T74268 |
STING agonist-13
|
||
STINGagonist-13 是一种STING 激动剂,通过STING 介导的免疫激活进行癌症免疫。STINGagonist-13 可刺激STING 下游信号传导并促进 I 型干扰素免疫反应。STINGagonist-13 能显著降低肿瘤体积并具有免疫记忆衍生的癌症抑制活性。 | |||
T38117 |
WSP-5
Washington State Probe-5,WSP-5 |
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Hydrogen sulfide (H2S) is an important gaseous mediator, like nitric oxide, that has significant effects on the immunological, neurological, cardiovascular and pulmonary systems of mammals. WSP-5 is a reactive disulfide-containing, fluorescent probe designed for fast detection of H2S in biological samples and cells. Through a reaction-based fluorescent turn-on strategy, WSP-5 selectively and rapidly reacts with H2S, generating a fluorophore with excitation and emission maxima of 502 and 525 nm, ... | |||
T62703 |
NTPDase-IN-2
|
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NTPDase-IN-2 (化合物 5g) 是一种具有选择性的NTPDase 抑制剂,其对h-NTPDase-2/-8的IC50值分别为 0.04 和 2.27 µM。NTPDase-IN-2 可非竞争性地抑制h-NTPDase-1/-2,其对h-NTPDase-2的Km 值为 74 µM。NTPDase-IN-2 可用于癌症、免疫学疾病以及细菌感染的研究。 | |||
T36666 |
Dehydro Warfarin
|
||
Dehydro warfarin is a metabolite of (±)-warfarin .1It is formed from (±)-warfarin by rat liver microsomes. 1.Kaminsky, L.S., Fasco, M.J., and Guengerich, F.P.Comparison of different forms of liver, kidney, and lung microsomal cytochrome P-450 by immunological inhibition of regio- and stereoselective metabolism of warfarinJ. Biol. Chem.254(19)9657-9662(1979) | |||
T64692 |
AMY-101 acetate
|
||
Complement component C3 plays a particularly versatile role in this process by keeping the cascade alert, acting as a point of convergence of activation pathways, fueling the amplification of the complement response, exerting direct effector functions, and helping to coordinate downstream immune responses[3]. In C3-/- mice alcohol-induced liver steatosis is absent or strongly reduced after chronic or acute alcohol exposure. This suggests that the complement system and its component C3 contribute... | |||
T37861 | Talabostat | ||
Talabostat (PT100, Val-boroPro) is a potent, nonselective and orally available dipeptidyl peptidase IV (DPP-IV) inhibitor with a Ki of 0.18 nM. Talabostat is a nonselective DPP-IV inhibitor, inhibiting DPP8/9, FAP, DPP2 and some other DASH family enzymes essentially as potently as it inhibits DPP-IV[1]. Talabostat stimulates the immune system by triggering a proinflammatory form of cell death in monocytes and macrophages known as pyroptosis. The inhibition of two serine proteases, DPP8 and DPP9,... |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T7851 |
Tyramine hydrochloride
盐酸酪胺,酪胺盐酸盐 |
Others; Endogenous Metabolite | Metabolism; Others |
Tyramine hydrochloride 是一种氨基酸,有助于调节血压。其中 Tyramine 天然存在于体内,并存在于某些食物中。 | |||
T2749 |
Ginkgolide A
银杏内酯A,BN-52020 |
GABA Receptor; Endogenous Metabolite | Membrane transporter/Ion channel; Metabolism; Neuroscience |
Ginkgolide A (BN-52020) 是从银杏叶提取出来的一种天然产物,是 GABA 拮抗剂,有用于多种炎症和免疫疾病的研究潜力。 | |||
TN4921 | Rubelloside B | ||
Rubelloside B exhibits immunological enhancement effect. |