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抑制剂 & 化合物

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Cat. No. Product Name Target Signaling Pathways
T124492 Imipenem

N-Formimidoyl thienamycin,MK0787

Antifungal Microbiology/Virology
Imipenem (MK0787) 是一种噻吩霉素衍生物,属于抗生素类,具有抗菌活性,对革兰氏阳性和革兰氏阴性菌具有部分的抑制作用。Imipenem 可用于研究碳青霉烯类非易感性感染和铜绿假单胞菌生物膜感染。
T4017 Relebactam

瑞来巴坦,MK-7655

Antibacterial Microbiology/Virology
Relebactam (MK-7655) 是一种有广谱抗β内酰胺酶活性的二氮杂双环辛烷抑制剂。
T2583 Cilastatin

西司他丁,MK0791

Proteasome; Antibacterial; Antibiotic Microbiology/Virology; Proteases/Proteasome; Ubiquitination
Cilastatin (MK0791) 是一种可逆的竞争性的肾脏脱氢肽酶 I 抑制剂,IC50为 0.1 μM。它抑制细菌金属叶内酰胺酶CphA 的IC50为 178 μM,可用作抗菌辅助剂。
T6411 Biapenem

CLI 86815,比阿培南,Biapenern,Omegacin,L 627,LJC 10627

Antibacterial; Antibiotic Microbiology/Virology
Biapenem (CLI 86815) 是不经肠道的广谱碳青霉烯抗生素。
T61173 Metallo-β-lactamase-IN-5

Metallo-β-lactamase-IN-5 (compound 5c) is a powerful inhibitor of metallo-β-lactamases (MBLs). Its inhibitory activity against MBLs NDM-1 and VIM-1 has been demonstrated. With an IC50 value of 45 μg/mL, Metallo-β-lactamase-IN-5 effectively inhibits HUVECs. Additionally, when combined with Imipenem, Metallo-β-lactamase-IN-5 exhibits synergistic antimicrobial activity [1].
T28314 PD 117588

PD117588,PD-117588

PD 117588 is a quinolone against bacterial isolates from cancer patients. PD 117558 has a broad antimicrobial spectrum with excellent activity against all Gram-positive isolates (including methicillin-resistant Staphylococcus aureus, coagulase-negative st

化合物

Imipenem
Cat.No: T124492
Synonym: N-Formimidoyl thienamycin,MK0787
Target: Antifungal
Relebactam
Cat.No: T4017
Synonym: 瑞来巴坦,MK-7655
Target: Antibacterial
Cilastatin
Cat.No: T2583
Synonym: 西司他丁,MK0791
Target: Proteasome, Antibacterial, Antibiotic
Biapenem
Cat.No: T6411
Synonym: CLI 86815,比阿培南,Biapenern,Omegacin,L 627,LJC 10627
Target: Antibacterial, Antibiotic
Metallo-β-lactamase-IN-5
Cat.No: T61173
Synonym:
Target:
PD 117588
Cat.No: T28314
Synonym: PD117588,PD-117588
Target:
Cat. No. Product Name Target Signaling Pathways
T1505 Imipenem monohydrate

N-Formimidoyl thienamycin monohydrate,亚胺培南,Imipenem,亚胺培南一水物

Antibacterial; Antibiotic Microbiology/Virology
Imipenem monohydrate (Imipenem) 是从微生物 Streptomyces cattleya 分离得到的碳青霉烯类抗生素,是一种用于静脉注射的β 内酰胺类抗生素,作用于细菌细胞壁,能广泛有效抑制多种革兰氏阳性和阴性菌。

天然产物

Imipenem monohydrate
Cat.No: T1505
Synonym: N-Formimidoyl thienamycin monohydrate,亚胺培南,Imipenem,亚胺培南一水物
Target: Antibacterial, Antibiotic
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