Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T6107 |
IU1
|
DUB; Autophagy | Autophagy; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Ubiquitination |
IU1 是一种可逆的特异性人类 USP14 蛋白酶体抑制剂,可以穿透细胞,IC50为 4.7 μM。 | |||
T15604 |
IU1-47
|
DUB | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Ubiquitination |
IU1-47 是一种特异性 USP14抑制剂,IC50为 0.6 μM。它诱导培养的神经元中 tau 蛋白降解。它抑制 IsoT/USP5, IC50为 20 μM。 | |||
T9375 |
IU1-248
|
DUB | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Ubiquitination |
IU1-248 是 IU1 的衍生物,是一种选择性 USP14 抑制剂,IC50 为 0.83 μM。 | |||
T35500 |
3-epi-25-hydroxy Vitamin D3
3-epi-25-hydroxy Vitamin D3 |
||
3-epi-25-hydroxy Vitamin D3is the C-3 epimer of 25-hydroxy vitamin D3.1Dietary administration of 3-epi-25-hydroxy vitamin D3(0.5 and 1 IU/g) decreases levels of serum parathyroid hormone (PTH) in male, but not female, weanling rats. 1.Djekic-Ivankovic, M., Lavery, P., Agellon, S., et al.The C-3α epimer of 25-hydroxycholecalciferol from endogenous and exogenous sources supports normal growth and bone mineral density in weanling ratsJ. Nutr.147(2)141-151(2017) |