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Cat. No.	Product Name	Target	Signaling Pathways
T2502	INH1 IBT13131	Apoptosis; Microtubule Associated	Apoptosis; Cytoskeletal Signaling
	INH1 (IBT13131) 通过直接结合Hec1，特异性干扰 Hec1/Nek2 的相互作用。它在体内外均表现出良好的抗肿瘤活性。
T74906	ODN 20844
	ODN 20844，鸟嘌呤修饰的抑制性寡核苷酸 (INH-ODN)，是一种 TLR7和TLR9(Toll-like receptor) 的抑制剂，其亲本为 INH-ODN 2088。ODN 20844 可以破坏TLR7和TLR9介导的免疫细胞免疫反应。ODN 20844 序列：5'-TCCTGGCGc7GGGAAGT-3'。
T79561	Mtb-IN-5
	Mtb-IN-5（化合物(-)17j）是一种异恶唑类化合物，对结核分枝杆菌(Mtb)具有活性。它能够抑制宿主巨噬细胞内Mtb的呼吸及生物膜生长，且能够增强异烟肼(INH)对耐INH Mtb突变株的抑制效果。
T74912	ODN 24991
	ODN 24991，鸟嘌呤修饰的抑制性寡核苷酸 (INH-ODN)，是一种 TLR3、TLR7和 TLR9(Toll-like receptor) 的抑制剂，其亲本为 INH-ODN 2088。ODN 24991 破坏了 TLR3、TLR7 和 TLR9介导的免疫细胞免疫反应。ODN 24991 序列：5'-C-C-T-G-G-C-c7rGm-G-G-G-3'。
T79559	Mtb-IN-4
	Mtb-IN-4（化合物17h）是一种异恶唑类化合物，显示出针对结核分枝杆菌（Mtb）的抗活性，其IC50值为0.70 μM。它能阻断巨噬细胞内Mtb的呼吸和生物膜形成，并可以增强抗生素异烟肼（INH）对耐INH Mtb突变体的抑制效果。
T74873	ODN 105871
	ODN 105871，一种G修饰的抑制性寡核苷酸(INH-ODN)，作为选择性TLR7抑制剂，适用于炎症免疫反应的研究。
T74872	ODN 105870
	ODN 105870 是一种 G 修饰的抑制性寡核苷酸 (INH-ODN)，是一种选择性 TLR7抑制剂。ODN 105870 可用于炎症免疫反应研究。
T38073	Thiocarlide Isoxyl
	Thiocarlide (isoxyl) is a thiourea derivative that was used in the 1960s to successfully treat tuberculosis (TB). It has considerable antimycobacterial activity in vitro and is effective against multi-drug resistant strains of Mycobacterium tuberculosis in the range of 1-10 &#181g/ml. [1] [2] At concentrations of 10 &#181M, isoxyl inhibits the synthesis of M. bovis during six hours of exposure which is similar to isoniazid (INH) and ethionamide (ETH), two other predominant anti-tuberculosis drug...
T35883	RNF5 inhibitor inh-02 RNF5 inhibitor inh-02
	RNF5 inhibitor inh-02, a potent E3 ubiquitin ligase RNF5/RMA1 inhibitor, demonstrates significant efficacy in rescuing F508del-CFTR with an EC50 of 2.2 uM in bronchial epithelial cells homozygous for the F508del mutation. This compound is valuable for cystic fibrosis research[1].
T74910	ODN 24888
	ODN 24888 是一种鸟嘌呤修饰的抑制性寡核苷酸 (INH-ODN)，对TLR7/TLR9介导的信号通路表现出强烈的抑制作用。ODN 24888 损害 IFN-α 水平和NF-κB 激活，抑制IL-6的释放。ODN 24888 参与免疫和炎症应答，可作为疫苗佐剂使用。
T74907	ODN 21595
	ODN 21595是一种鸟嘌呤修饰的抑制性寡核苷酸(INH-ODN)。该化合物能够抑制IFN-α和IL-6的释放，同时不具有细胞毒性。它还能降低CD86与HLA-DR的表达，显示出对于研究系统性红斑狼疮(SLE)具有潜力。
T37880	OPC-167832
	OPC-167832 is a potent and orally active dprE1 Inhibitor with an IC50 of 0.258 μM. OPC-167832 has antituberculosis activity and can be used for the research of tuberculosis caused by Mycobacterium tuberculosis[1]. OPC-167832 exhibits very low MICs against laboratory strains of M. tuberculosis H37Rv (MIC: 0.0005 μg/ml) and Kurono (MIC: 0.0005 μg/ml) and strains with monoresistance to rifampin (RIF), isoniazid (INH), ethambutol (EMB), streptomycin (STR), and pyrazinamide (PZA) (MIC: 0.00024-0.001 ...