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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T36526 |
IL-17 modulator 4
|
Interleukin | Immunology/Inflammation |
IL-17 modulator 4 是 IL-17 modulator 1 的前药,IL-17 modulator 1 是 IL-17 的有效调节剂。 | |||
T4050 |
GSK2981278
ROR gama modulator 1 |
ROR | Metabolism |
GSK2981278 (ROR gama modulator 1) 是 RORγ的选择性反向激动剂。它能够抑制 il17启动子的激活,并且干扰 RORγ-DNA 结合。 | |||
T40127 |
IL-17 modulator 3
|
||
IL-17 modulator 3 (US20200247785A1) is a chemical compound that acts as an IL-17 modulator. It has potential applications in researching inflammation, cancer, and autoimmune diseases. | |||
T40106 |
IL-17 modulator 1
|
||
IL-17 modulator 1 is an orally active small molecule. It is highly efficacious in modulating IL-17 and can effectively prevent, treat, or ameliorate various diseases such as psoriasis, ankylosing spondylitis, and psoriatic arthritis. | |||
T36525 |
IL-17 modulator 1 disodium
|
||
IL-17 Modulator 1 (disodium) is a potent, orally active compound, known for its high efficacy in modulating IL-17. This compound is extensively utilized for researching various diseases such as psoriasis, ankylosing spondylitis, and psoriatic arthritis[1]. | |||
T40107 | IL-17 modulator 4 sulfate | ||
IL-17 modulator 4 sulfate is a prodrug of IL-17 modulator 1 . IL-17 modulator 1 is an orally active, highly efficacious IL-17 modulator. | |||
T4670 |
SR0987
|
ROR | Metabolism |
SR0987是SR1078 的类似物,是RORγt 的激动剂,其EC50=800 nM。它可上调IL17 的表达,并且抑制PD-1 的表达。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-00470 |
IL-17A & IL-17F Heterodimer Protein, Human, Recombinant (His)
interleukin 17A,IL-17,IL... |
Human | HEK293 Cells |
IL-17A & IL-17F Heterodimer Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31 kDa and the accession number is NP_002181.1&NP_443104.1. | |||
TMPY-00053 |
IL-17A & IL-17F Heterodimer Protein, Human, Recombinant
CTLA8,IL17,IL-17,IL<... |
Human | E. coli |
IL-17A & IL-17F Heterodimer Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 30.7 kDa and the accession number is Q16552&NP_443104.1. | |||
TMPY-02900 |
IL-17A Protein, Mouse, Recombinant
IL-17A,Ctla8,Ctla-8,interleukin 17 |
Mouse | E. coli |
IL-17A Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 15.5 kDa and the accession number is Q62386. | |||
TMPY-02886 |
IL-17A Protein, Human, Recombinant
IL-17,白细胞介素,interleukin 17A,CTLA8... |
Human | E. coli |
IL-17A Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 15.7 kDa and the accession number is Q16552. | |||
TMPJ-01172 |
IL-17 Protein, Mouse, Recombinant (His)
CTLA8,IL-17,IL-17A,Inter... |
Mouse | HEK293 Cells |
Interleukin-17 is a potent pro-inflammatory cytokine produced by activated memory T cells. There are at least six members of the IL-17 family in humans and in mice. Mature mouse IL-17A shares 61% and 89% amino acid sequence identity with human and rat IL-17A, respectively. As IL-17 shares properties with IL-1 and TNF-alpha, it may induce joint inflammation and bone and cartilage destruction. This cytokine is found in synovial fluids of patients with rheumatoid arthritis, and produced by rheumato... | |||
TMPK-01036 |
IL-17A Protein, Mouse, Recombinant (His & Avi)
interleukin 17A,IL17A,CTLA-8,... |
Mouse | HEK293 Cells |
IL-17A Protein, Mouse, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 18 kDa and the accession number is Q62386-1. | |||
TMPY-02573 |
IL-17RC Protein, Human, Recombinant (aa 1-454, His)
IL17RL,interleukin 17 receptor C,... |
Human | Baculovirus Insect Cells |
IL-17RC Protein, Human, Recombinant (aa 1-454, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 49.6 kDa and the accession number is Q8NAC3-3. | |||
TMPK-01266 |
IL-17A Protein, Cynomolgus, Recombinant (His & Avi)
IL17,interleukin 17A,IL<... |
Cynomolgus | HEK293 Cells |
IL-17A Protein, Cynomolgus, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 18.2 kDa and the accession number is A0A2K5TTB0. | |||
TMPK-00975 |
IL-17A Protein, Human, Recombinant (His & Avi), Biotinylated
IL-17CTLA-8,interleukin 17A,CTLA-... |
Human | HEK293 Cells |
IL-17A Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 18.2 kDa and the accession number is Q16552-1. | |||
TMPK-01037 |
IL-17A Protein, Mouse, Recombinant (His & Avi), Biotinylated
IL17A,interleukin 17A,IL... |
Mouse | HEK293 Cells |
IL-17A Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 18 kDa and the accession number is Q62386-1. | |||
TMPY-02691 |
IL-17RC Protein, Human, Recombinant(aa 1-454, hFc)
IL17RL,interleukin 17 receptor C,... |
Human | HEK293 Cells |
IL-17RC Protein, Human, Recombinant(aa 1-454, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 75.3 kDa and the accession number is Q8NAC3-3. | |||
TMPY-04332 |
IL-17A Protein, Human, Recombinant (T26A, His)
CTLA-8,CTLA8,IL-17A,interleukin 17 |
Human | Baculovirus Insect Cells |
IL-17A Protein, Human, Recombinant (T26A, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 17.2 kDa and the accession number is Q16552. | |||
TMPY-05183 |
IL-17A Protein, Human, Recombinant, Biotinylated
interleukin 17A,IL-17,白细胞介素,白介素,<... |
Human | E. coli |
IL-17A Protein, Human, Recombinant, Biotinylated is expressed in E. coli expression system. The predicted molecular weight is 15.7 kDa and the accession number is Q16552. | |||
TMPY-03568 |
IL-17A Protein, Human, Recombinant (His)
CTLA-8,CTLA8,白介素,interleukin 17A,IL17<... |
Human | P. pastoris (Yeast) |
IL-17A Protein, Human, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 17.3 kDa and the accession number is Q16552. | |||
TMPJ-01444 |
IL-17A Protein, Cynomolgus, Recombinant (His)
CTLA-8,CTLA8,IL17A,IL-17... |
Cynomolgus | HEK293 Cells |
Interleukin-17 is a potent pro-inflammatory cytokine produced by activated memory T cells. There are at least six members of the IL-17 family in humans and in mice. As IL-17 shares properties with IL-1 and TNF-alpha, it may induce joint inflammation and bone and cartilage destruction. This cytokine is found in synovial fluids of patients with rheumatoid arthritis, and produced by rheumatoid arthritis synovium. It increases IL-6 production, induces collagen degradation and decreases collagen synt... | |||
TMPY-00855 |
IL-25/IL17E Protein, Mouse, Recombinant (His)
interleukin 25,IL-17e,Il17 |
Mouse | HEK293 Cells |
IL-25/IL17E Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20 kDa and the accession number is Q8VHH8. | |||
TMPY-00843 |
IL-25/IL17E Protein, Human, Recombinant (hFc)
interleukin 25,IL17E |
Human | HEK293 Cells |
IL-25/IL17E Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 45 kDa and the accession number is Q9H293-1. | |||
TMPJ-00060 |
IL-25/IL17E Protein, Human, Recombinant (His)
白细胞介素,IL17E,白介素,IL-17E,<... |
Human | HEK293 Cells |
Interleukin 25 (IL-25) belongs to the Interleukin 17 (IL-17) family of proteins, which is comprised of six members (IL-17, IL-17B through IL-17F). These proteins are secreted and are structurally related by sharing a conserved cysteine-knot fold near the C-terminus, but have considerable sequence divergence at the N-terminus. With the exception of IL-17B, which exists as a non-covalently linked dimer, all IL-17 family members are disulfide-linked dimers. IL-17 family proteins are pro-inflammator... | |||
TMPY-05563 |
IL-25/IL17E Protein, Canine, Recombinant (hFc)
interleukin 25,白细胞介素,白介素 |
Canine | HEK293 Cells |
IL-25/IL17E Protein, Canine, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 46.2 kDa and the accession number is A0A8I3MRV2. | |||
TMPY-03204 |
IL-25/IL17E Protein, Rat, Recombinant (hFc)
白介素,白细胞介素,interleukin 25 |
Rat | HEK293 Cells |
IL-25/IL17E Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 46.1 kDa and the accession number is D3ZLB1. | |||
TMPJ-00351 |
IL-23R Protein, Human, Recombinant (aa 24-353, hFc)
IL-23 receptor,IL23R,Interleukin-23 recept... |
Human | HEK293 Cells |
Interleukin 23 receptor (IL23R) is a type I cytokine receptor for IL23. IL23 receptor complex is comprised of two subunits, the IL12Rβ1 subunit, which is shared with several cytokines, and a subunit that is unique to IL-23. IL23, after binding to IL23R, activates memory T cells and mediates pro-inflammatory activities in part by the production of IL17 through activation of TH17 lymphocytes. IL23R is expressed on T cells, NK cells, dendritic cells, and macrophages. In fact, polymorphisms of the I... | |||
TMPJ-01219 |
IL-23R Protein, Mouse, Recombinant (hFc)
Il23r,IL-23R,interleukin 23 receptor,Inter... |
Mouse | HEK293 Cells |
Interleukin 23 receptor (IL23R), a heterodimer of the IL12 receptor β1 (IL12Rβ1) and IL12Rβ2, is a type I cytokine receptor for IL23. IL23R is comprised of two subunits, the IL12Rβ1 subunit, which is shared with several cytokines, and a subunit that is unique to IL-23. IL23, after binding to IL23R, activates memory T cells and mediates pro-inflammatory activities in part by the production of IL17 through activation of TH17 lymphocytes. IL23R is expressed on T cells, NK cells, dendritic cells, an... | |||
TMPH-02841 |
Prohibitin Protein, Mouse, Recombinant (His)
|
Mouse | E. coli |
Protein with pleiotropic attributes mediated in a cell-compartment- and tissue-specific manner, which include the plasma membrane-associated cell signaling functions, mitochondrial chaperone, and transcriptional co-regulator of transcription factors in the nucleus. Plays a role in adipose tissue and glucose Homeostasis in a sex-specific manner. Contributes to pulmonary vascular remodeling by accelerating proliferation of pulmonary arterial smooth muscle cells.; In the mitochondria, together with... |