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抑制剂 & 化合物

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T60920	PDE4-IN-8
	PDE4-IN-8 (Example 5) 是磷酸二酯酶4(PDE4)的有效抑制剂。PDE4-IN-8 对 PDE4B2 的 IC50值为 0.93 nM。然而，PDE4-IN-8 对 IL13、IL4、IFNy 的抑制作用微弱，IC50值分别为 4.04 nM, 36.33 nM, 2394 nM。

化合物

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Cat. No.	Product Name	Species	Expression System
TMPJ-00889	IL-13 Protein, Mouse, Recombinant (aa 22-131, His) T-Cell Activation Protein P600,IL-13,白细胞介素...	Mouse	HEK293 Cells
	IL-13 Protein, Mouse, Recombinant (aa 22-131, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 14-30 KDa and the accession number is P20109.
TMPJ-00890	IL-13 Protein, Mouse, Recombinant (aa 26-131, His) Interleukin-13,T-Cell Activation Protein P600,白细胞介素...	Mouse	HEK293 Cells
	IL-13 Protein, Mouse, Recombinant (aa 26-131, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 15-30 KDa and the accession number is P20109.
TMPJ-00575	IL-13 Protein, Human, Recombinant (His) Interleukin-13,IL-13,白介素,白细胞介素	Human	HEK293 Cells
	IL-13 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 13-30 KDa and the accession number is AAH96139.
TMPK-00617	IL-13 Protein, Human, Recombinant (His & Avi) NC30,ALRH,IL13,MGC116786,MGC116789,P600,MG...	Human	HEK293 Cells
	Interleukin-13 (IL-13) is a monomeric 17 kDa immunoregulatory cytokine that plays a key role in the pathogenesis of allergy, cancer, and tissue fibrosis. It is secreted by several helper T cell subsets, NK cells, mast cells, eosinophils, basophils, and visceral smooth muscle cells. Inhibits inflammatory cytokine production. Synergizes with IL2 in regulating interferon-gamma synthesis. May be critical in regulating inflammatory and immune responses. Positively regulates IL31RA expression in macro...
TMPY-01993	IL-13 Protein, Human, Recombinant IL-13,P600,interleukin 13,ALRH,白介...	Human	CHO Cells
	IL-13 Protein, Human, Recombinant is expressed in CHO mammalian cells. The predicted molecular weight is 12.5 kDa and the accession number is AAK53823.1.
TMPY-00840	IL-13 Protein, Human, Recombinant (hFc) IL-13,白介素,白细胞介素,ALRH,interleukin 13	Human	HEK293 Cells
	IL-13 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 39 kDa and the accession number is AAK53823.1.
TMPJ-00596	IL-13 Protein, Human, Recombinant (mFc) Interleukin-13,白介素,IL-13,白细胞介素	Human	HEK293 Cells
	IL-13 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with C-mFc tag. The predicted molecular weight is 38-60 KDa and the accession number is AAK53823.
TMPJ-00594	IL-13 Protein, Human, Recombinant (Avi & His), Biotinylated Interleukin-13,白细胞介素,IL-13,白介素	Human	HEK293 Cells
	IL-13 Protein, Human, Recombinant (Avi & His), Biotinylated is expressed in HEK293 mammalian cells with C-Avi-6xHis tag. The predicted molecular weight is 22-35 KDa and the accession number is AAK53823.
TMPJ-00387	IL-4R alpha Protein, Mouse, Recombinant (hFc) Soluble IL-4R-alpha,Interleukin-4 receptor subunit ...	Mouse	HEK293 Cells
	Interleukin-4 receptor subunit alpha(IL-4RA), alos known as Soluble IL-4 receptor subunit alpha, belongs to the type I cytokine receptor family and type 4 subfamily. It expressed in both Th1 and Th2 cells. It functions as receptor for both interleukin 4 and interleukin 13 and couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and chemokine and mucus production at sites of allergic ...
TMPH-03116	IL-4R Protein, Pig, Recombinant (His)	Sus scrofa (Pig)	E. coli
	Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammation. In certain cell types, can signal through activation of insulin receptor substrates, IRS1/IRS2. IL-4R Protein, Pig, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted mo...
TMPJ-00270	IL-13RA1 Protein, Mouse, Recombinant (His & Avi), Biotinylated Interleukin-13 receptor subunit α-1,NR4,Interleukin...	Mouse	HEK293 Cells
	Interleukin-13 receptor subunit alpha-1(IL-13RA1), also known as NR4, belongs to the hemopoietin receptor family. Interleukin-13 receptor is a complex of IL4R, IL13RA1, and possibly other components. It interacts with TRAF3IP1 and binds with low affinity to interleukin-13(IL3). IL-13RA1, together with IL4RA, can form a functional receptor for IL13. It also serves as an alternate accessory protein to the common cytokine receptor gamma chain for interleukin-4 (IL4) signaling, but cannot replace th...