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Cat. No. Product Name Target Signaling Pathways
T14943 CGP60474

VEGFR; CDK; PKC Angiogenesis; Cell Cycle/Checkpoint; Chromatin/Epigenetic; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors
CGP60474 是一种高效的抗内毒素药物,抑制细胞周期蛋白依赖激酶(CDK) ,抑制 CDK1/B、CDK2/E、CDK2/a、CDK4/D、CDK5/p25、CDK7/H 和 CDK9/T 的IC50分别为 26、3、4、216、10、200 和 13 nM。它是选择性和 ATP 竞争性PKC 抑制剂。
T11357 Gamma-glutamylcysteine TFA

γ-glutamylcysteine (TFA),Gamma-glutamylcysteine (TFA)

IL Receptor Immunology/Inflammation
Gamma-glutamylcysteine (TFA) also upregulates the level of the anti-inflammatory cytokine IL-10 and reduces the levels of the pro-inflammatory cytokines (TNF-α, IL-6, and IL-1β) and attenuates the changes in metalloproteinase activity in oligomeric Aβ40-treated astrocytes. Gamma-glutamylcysteine (TFA) ((γ-glutamylcysteine (TFA)), an intermediate in glutathione (GSH) synthesis, is a dipeptide served as an essential cofactor for the antioxidant enzyme glutathione peroxidase (GPx).

化合物

CGP60474
Cat.No: T14943
Synonym:
Target: VEGFR, CDK, PKC
Gamma-glutamylcysteine TFA
Cat.No: T11357
Synonym: γ-glutamylcysteine (TFA),Gamma-glutamylcysteine (TFA)
Target: IL Receptor
TargetMol Loading
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