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Search Results for " il-32 "

Targets Recommended: Epigenetic Reader Domain Histone Acetyltransferase

3

抑制剂 & 化合物

2

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T6668	SGC-CBP30	Epigenetic Reader Domain; Histone Acetyltransferase	Chromatin/Epigenetic
	SGC-CBP30 是高选择性CBP/p300溴结构域的有效抑制剂，对CBP 和p300的Kd 值分别为 21 和 32 nM。它强烈减少 Th17 细胞中 IL-17A 的分泌，具有抗炎作用。
T63088	NOD2 antagonist 1
	NOD2 antagonist 1 (compound 32) 是一种有效的、选择性的 NOD2 拮抗剂 (IC50: 5.23 μM)。NOD2 antagonist 1 在 THP-1 细胞，对 Muramyl dipeptide (MDP) 诱导的 IL-8 分泌表现出抑制作用。NOD2 antagonist 1 在 PBMCs 细胞，可以抑制 MDP 诱导的 IL-6、IL-10 和 TNF-α 的水平升高。
T35450	α-GalCer analog 8 α-GalCer analog 8,α-Galactosylceramide analog 8
	α-Galactosylceramide analog 8 (α-GalCer analog 8) is a triazole derivative of α-galactosylceramide. [1] It increases IL-2 secretion by DN32.D3 NKT hybridoma cells when co-cultured with CD1d-transfected RBL cells pre-loaded with α-GalCer analog 8 at a concentration of 32 ng/ml. α-GalCer analog 8 (32 ng/ml) induces IL-4 secretion to a greater extent than the synthetic α-GalCer KRN 7000 in mouse splenocytes in vitro and in mouse serum following administration of a 1 &#181g per animal dose, indicati...

化合物

Cat.No: T6668

Target: Epigenetic Reader Domain, Histone Acetyltransferase

NOD2 antagonist 1

Cat.No: T63088

α-GalCer analog 8

Cat.No: T35450

Synonym: α-GalCer analog 8,α-Galactosylceramide analog 8

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-01033	IL-32 Protein, Human, Recombinant (isoform alpha, His) IL-32δ,IL-32beta,IL<...	Human	HEK293
	IL-32 is a recently discovered cytokine that induces various proinflammatory cytokines (TNF-alpha, IL-1beta, IL-6) and chemokines in both human and mouse cells through the NF-kappaB and p38 MAPK inflammatory signal pathways. It is regulated robustly by other major proinflammatory cytokines and is crucial to inflammation and immune responses. Four of the IL-32 isoforms (alpha, beta, gamma, and delta) are the most representative IL-32 transcripts, and the gamma isoform of IL-32 is the most active,...
TMPY-04561	SGK3 Protein, Human, Recombinant (His & GST) serum/glucocorticoid regulated kinase family, membe...	Human	Baculovirus-Insect Cells
	Serine / threonine-protein kinase Sgk3, also known as Serum / glucocorticoid-regulated kinase 3, Serum / glucocorticoid-regulated kinase-like and SGK3, is a cytoplasmic vesicle protein that belongs to the protein kinase superfamily and AGC Ser/Thr protein kinase family. SGK3 contains one AGC-kinase C-terminal domain, one protein kinase domain and one PX (phox homology) domain. Two specific sites of SGK3, one in the kinase domain (Thr-32) and the other in the C-terminal regulatory region (Ser-486...

重组蛋白

IL-32 Protein, Human, Recombinant (isoform alpha, His)

Cat.No: TMPY-01033

Species: Human

Expression System: HEK293

SGK3 Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-04561

Species: Human

Expression System: Baculovirus-Insect Cells

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