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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T14369 |
AZD-0284
|
ROR | Metabolism |
AZD-0284 是核受体 (RORγ) 的选择性反向激动剂。它对呼吸道疾病及斑块型寻常型银屑病具有潜在的应用价值。 | |||
T76798 |
Bimekizumab
|
||
Bimekizumab (Anti-Human IL17A/IL-17F Recombinant Antibody) 是一种人源化单克隆抗体,可选择性中和 IL-17A 和 IL-17F。这两种细胞因子都能够促进成骨的人骨膜衍生细胞 (hPDC) 分化。因此,Bimekizumab 的应用,可以阻断炎症驱动的成骨分化。 | |||
T76901 | Afasevikumab | ||
Afasevikumab (RG 7624; RO 5553110; NI-1401) 是一种全人单克隆 IgG1κ 抗体,可中和 IL-17A 和 IL-17F。Afasevikumab 具有抗炎活性。 | |||
T79024 |
Androgen receptor-IN-5
|
Androgen Receptor | Endocrinology/Hormones |
Androgen Receptor-IN-5 为雄激素受体 (androgen receptor) 抑制剂,显示出有效的抗肿瘤活性。它亦能够抑制IL-17A、IL-17F及INF-γ的生成。 | |||
T76885 | Sonelokimab | ||
Sonelokimab (ALX 0761; M 1095) 是三价纳米抗体,特异性结合人白介素(IL)-17A、IL-17F及人血清白蛋白VHH,由单价骆驼来源纳米抗体构成,展现于斑块型银屑病研究中的应用潜力。 | |||
T13172L | TMP778 | Others | Others |
TMP778 is an effective and selective RORγt inverse agonist (IC50: 7 nM in FRET assay). |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-03802 |
IL-17F Protein, Human, Recombinant (aa 31-163)
ML1,ML-1,IL-17F,interleukin 17F,C... |
Human | E. coli |
IL-17F Protein, Human, Recombinant (aa 31-163) is expressed in E. coli expression system. The predicted molecular weight is 15.1 kDa and the accession number is AAH70124.1. | |||
TMPY-01966 |
IL-17F Protein, Mouse, Recombinant
IL-17F,C87042,interleukin 17F |
Mouse | E. coli |
IL-17F Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 15 kDa and the accession number is Q7TNI7-1. | |||
TMPY-01957 |
IL-17F Protein, Mouse, Recombinant (His)
IL-17F,interleukin 17F,C87042 |
Mouse | HEK293 Cells |
IL-17F Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 16.3 kDa and the accession number is Q7TNI7-1. | |||
TMPJ-00633 |
IL-17F Protein, Cynomolgus, Recombinant (His)
IL17F,Cytokine ML-1,IL-17F |
Cynomolgus | HEK293 Cells |
IL-17F Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 19-22 KDa and the accession number is G7P4V0. | |||
TMPJ-00573 |
IL-17F Protein, Human, Recombinant (His)
IL17F,IL-17F,Cytokine ML... |
Human | HEK293 Cells |
IL-17F Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 19 KDa and the accession number is AAH70124.1. | |||
TMPJ-00046 |
IL-17F Protein, Human, Recombinant
IL17F,白介素,IL-17F,Interle... |
Human | E. coli |
Interleukin-17 is a potent pro-inflammatory cytokine produced by activated memory T cells. There are at least six members of the IL-17 family in humans and in mice. Today, IL-17 represents a family of structurally related cytokines that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family, IL-17A through IL-17F, are secreted as homodimers. IL-17F also regulates cartilage mat... | |||
TMPY-01898 |
IL-17F Protein, Human, Recombinant (aa 31-163, His)
CANDF6,IL-17F,interleukin 17F,ML-... |
Human | HEK293 Cells |
IL-17F Protein, Human, Recombinant (aa 31-163, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.2 kDa and the accession number is Q96PD4. | |||
TMPY-05461 |
IL-17F Protein, Human, Recombinant (His), Biotinylated
ML-1,CANDF6,interleukin 17F,IL-17F |
Human | HEK293 Cells |
IL-17F Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 73.3 kDa and the accession number is Q96PD4. | |||
TMPK-00041 |
IL-17F Protein, Mouse, Recombinant (His & Avi)
IL-24,IL17F,ML1,IL-1... |
Mouse | HEK293 Cells |
IL-17F Protein, Mouse, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 17.8 kDa and the accession number is Q7TNI7-1. | |||
TMPK-00042 |
IL-17F Protein, Mouse, Recombinant (His & Avi), Biotinylated
CANDF6,ML1,Cytokine ML-1,IL17F,IL... |
Mouse | HEK293 Cells |
IL-17F Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 17.8 kDa and the accession number is Q7TNI7-1. | |||
TMPK-00046 |
IL-17F Protein, Human, Recombinant (His & Avi), Biotinylated
CANDF6,IL-24,IL24,IL17F,... |
Human | HEK293 Cells |
IL-17F Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 17.5 /14.9 kDa and the accession number is Q96PD4. | |||
TMPY-00053 |
IL-17A & IL-17F Heterodimer Protein, Human, Recombinant
CTLA8,IL17,IL-17,IL-17A,interleuk... |
Human | E. coli |
IL-17A & IL-17F Heterodimer Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 30.7 kDa and the accession number is Q16552&NP_443104.1. | |||
TMPY-00470 |
IL-17A & IL-17F Heterodimer Protein, Human, Recombinant (His)
interleukin 17A,IL-17,IL-17A,IL17... |
Human | HEK293 Cells |
IL-17A & IL-17F Heterodimer Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31 kDa and the accession number is NP_002181.1&NP_443104.1. | |||
TMPY-00460 |
IL-17F Protein, Rat, Recombinant (His)
interleukin 17F |
Rat | Baculovirus Insect Cells |
IL-17F Protein, Rat, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 16.4 kDa and the accession number is Q5BJ95. | |||
TMPY-04728 |
IL-17A & IL-17F Heterodimer Protein, Rhesus, Recombinant (His)
interleukin 17A |
Rhesus | HEK293 Cells |
IL-17A & IL-17F Heterodimer Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 32.5 kDa and the accession number is XP_001106391.1&NP_001248216.1. | |||
TMPJ-01237 |
IL-17D Protein, Human, Recombinant
IL17D,Interleukin-17D,IL-17D |
Human | E. coli |
The Interleukin-17 family proteins, comprising six members (IL-17, IL-17B through IL-17F),are secreted, structurally related proteins that share a conserved cysteine-knot fold near the C-terminus, but have considerable sequence divergence at the N-terminus. IL-17 family proteins are proinflammatory cytokines that induce local cytokine production and are involved in the regulation of immune functions. Among IL-17 family members, IL-17D is most closely related to IL-17B, sharing 27% aa sequence ho... | |||
TMPJ-00060 |
IL-25/IL17E Protein, Human, Recombinant (His)
白细胞介素,IL17E,白介素,IL-17E,IL-25,... |
Human | HEK293 Cells |
Interleukin 25 (IL-25) belongs to the Interleukin 17 (IL-17) family of proteins, which is comprised of six members (IL-17, IL-17B through IL-17F). These proteins are secreted and are structurally related by sharing a conserved cysteine-knot fold near the C-terminus, but have considerable sequence divergence at the N-terminus. With the exception of IL-17B, which exists as a non-covalently linked dimer, all IL-17 family members are disulfide-linked dimers. IL-17 family proteins are pro-inflammator... |