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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T22142 |
RO8191
RO4948191,CDM-3008 |
HCV Protease; HBV; JAK; IFNAR; STAT | Angiogenesis; Chromatin/Epigenetic; Immunology/Inflammation; JAK/STAT signaling; Microbiology/Virology; Proteases/Proteasome; Stem Cells |
RO8191 (CDM-3008) 是干扰素 (IFN) 受体激动剂。它直接与 IFNα/β 受体 2 结合,激活 IFN 刺激的基因表达和 JAK/STAT 磷酸化。它通过具有干扰素样活性发挥 cccDNA 调节剂作用,并具有抗 HBV 活性。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-04799 |
IFNAR2 Protein, Human, Recombinant (His), Biotinylated
IFN-R,interferon (α, β and Ω) receptor 2,IFNABR,int... |
Human | HEK293 Cells |
IFNAR2 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.2 kDa and the accession number is P48551-1. | |||
TMPK-00889 |
IFNAR2 Protein, Human, Recombinant (aa 27-243, His)
IFN-alpha/beta R2,IFNAR2,IFNbR |
Human | HEK293 Cells |
Although interferon (IFN)-α is known to exert immunomodulatory and antiproliferative effects on dendritic cells (DCs) through induction of protein-coding IFN-stimulated genes (ISGs), little is known about IFN-α-regulated miRNAs in DCs. Since several miRNAs are involved in regulating DC functions, it is important to investigate whether IFN-α's effects on DCs are mediated through miRNAs as well. IFNAR2 Protein, Human, Recombinant (aa 27-243, His) is expressed in HEK293 mammalian cells with C-His t... | |||
TMPK-00637 |
IFNAR2 Protein, Cynomolgus, Recombinant (aa 27-243, His)
β receptor10,IFNbR2,IFN α/β R2,IFN-R,I... |
Cynomolgus | HEK293 Cells |
Although interferon (IFN)-α is known to exert immunomodulatory and antiproliferative effects on dendritic cells (DCs) through induction of protein-coding IFN-stimulated genes (ISGs), little is known about IFN-α-regulated miRNAs in DCs. Since several miRNAs are involved in regulating DC functions, it is important to investigate whether IFN-α's effects on DCs are mediated through miRNAs as well. IFNAR2 Protein, Cynomolgus, Recombinant (aa 27-243, His) is expressed in HEK293 mammalian cells with C-... | |||
TMPY-01642 |
IFNAR2 Protein, Human, Recombinant (His)
IFNARB,IFNABR,interferon (α, β and ω) receptor ... |
Human | HEK293 Cells |
IFNAR2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.2 kDa and the accession number is P48551-1. | |||
TMPY-00139 |
IFNAR2 Protein, Cynomolgus, Recombinant (His)
interferon (α, β and Ω) receptor 2,interferon (alph... |
Cynomolgus | HEK293 Cells |
IFNAR2 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.3 kDa and the accession number is XP_005548871.1. | |||
TMPY-01640 |
IFNAR2 Protein, Human, Recombinant (hFc)
interferon (α, β and ω) receptor 2,IFNABR,IFN-R,int... |
Human | HEK293 Cells |
IFNAR2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 51.8 kDa and the accession number is P48551-1. | |||
TMPH-02732 |
IFNAR2 Protein, Mouse, Recombinant (His)
|
Mouse | P. pastoris (Yeast) |
Associates with IFNAR1 to form the plasma membrane receptor in the type I interferon signaling pathway. Directly involved in signal transduction through its association with the TYR kinase JAK1. Involved in interferon-mediated STAT1, STAT2 and STAT3 activation.; May be potent inhibitors of type I IFN receptor activity.; May be potent inhibitors of type I IFN receptor activity. IFNAR2 Protein, Mouse, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 26.8 ... |