首页工具

登录

搜索结果

Search Results for " ifn-r "

Targets Recommended: STAT

4

抑制剂 & 化合物

14

重组蛋白

如果没找到您满意的产品或者您对产品有其他要求，可以联系我们专业顾问为您提供针对性的合理建议。 QQ咨询网站留言咨询

Cat. No.	Product Name	Target	Signaling Pathways
T21694	(R)-Lisofylline (R)-Lisophylline	STAT	JAK/STAT signaling; Stem Cells
	(R)-Lisofylline ((R)-Lisophylline) 是溶血磷脂酸酰基转移酶的抑制剂 (IC50 = 0.6 µM)。 (R)-Lisofylline 可中断 IL-12 信号介导的 STAT4 激活，可用于治疗 1 型糖尿病和自身免疫性疾病的研究。
T38329	CU-76
	CU-76 is an inhibitor of cyclic GMP-AMP synthase (cGAS; IC50= 0.24 μM).1It reduces DNA-, but not Sendai virus-, induced dimerization of IFN regulatory factor 3 in THP-1 cells, indicating selectivity for the cGAS DNA sensing pathway over the RIG-I-MAVS RNA sensing pathway. CU-76 decreases IFN-stimulatory DNA-induced production of IFN-β in THP-1 cells when used at concentrations of 10, 30, and 100 μM. 1.Padilla-Salinas, R., Sun, L., Anderson, R., et al.Discovery of small-molecule cyclic GMP-AMP sy...
T38328	CU-32
	CU-32 is an inhibitor of cyclic GMP-AMP (cGAMP) synthase (cGAS; IC50= 0.45 μM).1It reduces DNA-, but not Sendai virus-, induced dimerization of IFN regulatory factor 3 in THP-1 cells, indicating selectivity for the cGAS DNA sensing pathway over the RIG-I-MAVS RNA sensing pathway. It is also selective for cGAS over toll-like receptors (TLRs) at 50 μM. CU-32 decreases IFN-stimulatory DNA-induced production of IFN-β in THP-1 cells when used at concentrations of 10, 30, and 100 μM. 1.Padilla-Salinas...
T38160	STING Agonist 1a
	STING agonist 1a is an agonist of stimulator of interferon genes (STING).1It induces expression of an IRF-inducible SEAP reporter gene in a cell-based assay (EC50= 16.77 μM). STING agonist 1a (12.5-100 μM) induces expression of IFN-β, IL-6, and chemokine (C-X-C motif) ligand 10 (CXCL10) in THP-1 cells, an effect that can be reversed by STING knockout or the STING inhibitor H-151 . 1.Hou, H., Yang, R., Liu, X., et al.Discovery of triazoloquinoxaline as novel STING agonists via structure-based vir...

化合物

(R)-Lisofylline

Cat.No: T21694

Synonym: (R)-Lisophylline

Target: STAT

Cat.No: T38329

Cat.No: T38328

STING Agonist 1a

Cat.No: T38160

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-04799	IFNAR2 Protein, Human, Recombinant (His), Biotinylated IFN-R,interferon (α, β a...	Human	HEK293 Cells
	IFNAR2 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.2 kDa and the accession number is P48551-1.
TMPK-00047	IFN gamma Protein, Human, Recombinant (His & Avi) IFN gamma,interferon,Inter	Human	HEK293 Cells
	Interferon-gamma (IFN gamma) is a cytokine that plays physiologically important roles in promoting innate and adaptive immune responses. The absence of IFN gamma production or cellular responsiveness in humans and experimental animals significantly predisposes the host to microbial infection, a result that validates the physiologic importance of this cytokine in preventing infectious disease. IFN gamma Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi ...
TMPK-00637	IFNAR2 Protein, Cynomolgus, Recombinant (aa 27-243, His) β receptor10,IFNbR2,...	Cynomolgus	HEK293 Cells
	Although interferon (IFN)-α is known to exert immunomodulatory and antiproliferative effects on dendritic cells (DCs) through induction of protein-coding IFN-stimulated genes (ISGs), little is known about IFN-α-regulated miRNAs in DCs. Since several miRNAs are involved in regulating DC functions, it is important to investigate whether IFN-α's effects on DCs are mediated through miRNAs as well. IFNAR2 Protein, Cynomolgus, Recombinant (aa 27-243, His) is expressed in HEK293 mammalian cells with C-...
TMPK-00889	IFNAR2 Protein, Human, Recombinant (aa 27-243, His) IFN-alpha/beta R2,IFNAR2...	Human	HEK293 Cells
	Although interferon (IFN)-α is known to exert immunomodulatory and antiproliferative effects on dendritic cells (DCs) through induction of protein-coding IFN-stimulated genes (ISGs), little is known about IFN-α-regulated miRNAs in DCs. Since several miRNAs are involved in regulating DC functions, it is important to investigate whether IFN-α's effects on DCs are mediated through miRNAs as well. IFNAR2 Protein, Human, Recombinant (aa 27-243, His) is expressed in HEK293 mammalian cells with C-His t...
TMPK-00326	IFNAR1, Protein, Human, Recombinant (His & Avi), Biotinylated IFN-alpha/β R1,IFN-α/β R...	Human	HEK293 Cells
	IFNAR1, Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 50.2 kDa and the accession number is P17181-1.
TMPK-00342	IFNAR1 Protein, Mouse, Recombinant (His & Avi) IFN-α-REC,IFN-R-1,IF...	Mouse	HEK293 Cells
	IFNAR1 Protein, Mouse, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 46.9 kDa and the accession number is P33896.
TMPK-00325	IFNAR1 Protein, Human, Recombinant (His & Avi) AVP,IFN-alpha-REC,IFN-α/β R	Human	HEK293 Cells
	IFNAR1 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 50.2 kDa and the accession number is P17181-1.
TMPK-00343	IFNAR1 Protein, Mouse, Recombinant (hFc) AVP,IFNBR,IFN-alpha/β R1...	Mouse	HEK293 Cells
	IFNAR1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 72.5 kDa and the accession number is P33896.
TMPY-01640	IFNAR2 Protein, Human, Recombinant (hFc) interferon (α, β and ω) recepto	Human	HEK293 Cells
	IFNAR2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 51.8 kDa and the accession number is P48551-1.
TMPY-01642	IFNAR2 Protein, Human, Recombinant (His) IFNARB,IFNABR,inter<...	Human	HEK293 Cells
	IFNAR2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.2 kDa and the accession number is P48551-1.
TMPK-00048	IFN gamma Protein, Human, Recombinant (His & Avi), Biotinylated IFNγ,IFN γ/IFNG,gamma,γ,IFG,I...	Human	HEK293 Cells
	Interferon-gamma (IFN gamma) is a cytokine that plays physiologically important roles in promoting innate and adaptive immune responses. The absence of IFN gamma production or cellular responsiveness in humans and experimental animals significantly predisposes the host to microbial infection, a result that validates the physiologic importance of this cytokine in preventing infectious disease. IFN gamma Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells w...
TMPY-02219	Influenza A H1N1 (A/Puerto Rico/8/34/Mount Sinai) Non-structural/NS1 Protein (His) NS1 Protein	H1N1	E. coli
	The NS1 Influenza protein is created by the internal protein-encoding, linear negative-sense, single-stranded RNA, NS gene segment and which also codes for the nuclear export protein or NEP, formerly referred to as the NS2 protein, which mediates the export of vRNPs. The non-structural (NS1) protein is found in Influenzavirus A, Influenzavirus B, and Influenzavirus C. The non-structural (NS1) protein of the highly pathogenic avian H5N1 viruses circulating in poultry and waterfowl in Southeast As...
TMPJ-01056	IL-18 Protein, Mouse, Recombinant (His) Interferon γ-inducing factor,Inte...	Mouse	E. coli
	Interleukin-18 (IL-18）is a protein which belongs to the IL-1 family. It is expressed as a 24 kDa precursor by endothelial and epithelial cells, keratinocytes, gamma δ T cells, and phagocytes. Mature mouse IL-18 shares 63% and 91% amino acid sequence identity with mouse and rat IL-18, respectively. IL-18 binds to the widely expressed IL-18 R alpha which recruits IL-18 R beta to form the signaling receptor complex. Its bioactivity is negatively regulated by interactions with IL-18 binding proteins...
TMPJ-01337	IL-21R Protein, Mouse, Recombinant (aa 20-236, His) Nilr,IL-21R,Interleukin-21 r<...	Mouse	HEK293 Cells
	Interleukin-21 receptor (IL-21R) is a type I transmembrane glycoprotein within the class I cytokine receptor family, type 4 subfamily. IL-21R is expressed mainly on B cells, NK cells, and activated T cells, but is also found on dendritic cells, alternatively activated macrophages, intestinal lamina propria fibroblasts and epithelial cells, and keratinocytes. Both IL-21 and IL-4 are necessary for efficient B cell IgG1 production and normal germinal center architecture. B cell IL-21 R engagement i...

重组蛋白

IFNAR2 Protein, Human, Recombinant (His), Biotinylated

Cat.No: TMPY-04799

Species: Human

Expression System: HEK293 Cells

IFN gamma Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00047

Species: Human

Expression System: HEK293 Cells

IFNAR2 Protein, Cynomolgus, Recombinant (aa 27-243, His)

Cat.No: TMPK-00637

Species: Cynomolgus

Expression System: HEK293 Cells

IFNAR2 Protein, Human, Recombinant (aa 27-243, His)

Cat.No: TMPK-00889

Species: Human

Expression System: HEK293 Cells

IFNAR1, Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00326

Species: Human

Expression System: HEK293 Cells

IFNAR1 Protein, Mouse, Recombinant (His & Avi)

Cat.No: TMPK-00342

Species: Mouse

Expression System: HEK293 Cells

IFNAR1 Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00325

Species: Human

Expression System: HEK293 Cells

IFNAR1 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPK-00343

Species: Mouse

Expression System: HEK293 Cells

IFNAR2 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-01640

Species: Human

Expression System: HEK293 Cells

IFNAR2 Protein, Human, Recombinant (His)

Cat.No: TMPY-01642

Species: Human

Expression System: HEK293 Cells

IFN gamma Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00048

Species: Human

Expression System: HEK293 Cells

Influenza A H1N1 (A/Puerto Rico/8/34/Mount Sinai) Non-structural/NS1 Protein (His)

Cat.No: TMPY-02219

Species: H1N1

Expression System: E. coli

IL-18 Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-01056

Species: Mouse

Expression System: E. coli

IL-21R Protein, Mouse, Recombinant (aa 20-236, His)

Cat.No: TMPJ-01337

Species: Mouse

Expression System: HEK293 Cells

我们的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。

Copyright © 2015-2024 TargetMol Chemicals Inc. All rights reserved. 沪ICP备20019793号-4

沪公网安备 31010602006700号

沪公网安备 31010602006700号

TargetMol Loading

联系我们

电话：

400-820-0310

邮箱：

service@tsbiochem.com

QQ：

2881945090（终端用户）

2885109491（经销商）

经销：

终端：

地址：

上海市静安区江场三路238号8楼