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Targets Recommended: Amino Acids and Derivatives VDAC ABC

7

抑制剂 & 化合物

6

天然产物

1

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T18975 DIDS sodium salt

4,4'-二异硫氰酸基-2,2'-二苯乙烯磺酸二钠[蛋白质改性试剂],MDL101114ZA

VDAC; ABC Membrane transporter/Ion channel
DIDS sodium salt (MDL101114ZA) 是有效的ABCA1和VDAC1双抑制剂。
T20694 DIDS

DIDS, an anion exchange inhibitor, acts by blocking reversibly and later irreversibly, exchangers such as chloride-bicarbonate exchanger. It is also a RAD51 inhibitor.
T40697 Glucocorticoids receptor agonist 2

Glucocorticoid receptor agonist 2 is a highly effective anti-inflammatory compound, derived from arylpyrazole, that actively binds to and activates the glucocorticoid receptor. This compound exhibits potent anti-inflammatory properties without disrupting insulin secretion.
T40808 Glucocorticoids receptor agonist 1

Glucocorticoids receptor agonist 1 (GRA-1) is a highly effective arylpyrazole-based compound that acts as an agonist for the glucocorticoid receptor. GRA-1 exhibits strong anti-inflammatory properties while maintaining insulin secretion function.
T13896 Soya fatty acids

Others Others
Soya fatty acids is a class of polyunsaturated fatty acids isolated from soybean.
T37691 Phosphatidic Acids (egg) (ammonium salt)

Phosphatidic acid is a phospholipid and an intermediate in glycerolipid biosynthesis. It is a transient intermediate in the synthesis of various phospholipid species that is synthesized de novo in cells via multiple routes, including the glycerol-3 phosphate and dihydroxyacetone phosphate pathways, enzymatic conversion of phosphatidylcholine by phospholipase D, and acetylation of lysophosphatidic acid by lysoPA-acyltransferase, among others. It has roles in shaping cellular membranes, cellular ...
TP1816 Urotensin II, mouse

Jump to search UTS2 Identifiers Aliases UTS2, PRO1068, U-II, UCN2, UII, urotensin 2 External IDs OMIM: 604097 MGI: 1346329 HomoloGene: 4939 GeneCards: UTS2 hide Gene location (Human) Chr. Chromosome 1 (human)[1] Band 1p36.23 Start 7,843,083 bp[1] En

化合物

DIDS sodium salt
Cat.No: T18975
Synonym: 4,4'-二异硫氰酸基-2,2'-二苯乙烯磺酸二钠[蛋白质改性试剂],MDL101114ZA
Target: VDAC, ABC
DIDS
Cat.No: T20694
Synonym:
Target:
Glucocorticoids receptor agonist 2
Cat.No: T40697
Synonym:
Target:
Glucocorticoids receptor agonist 1
Cat.No: T40808
Synonym:
Target:
Soya fatty acids
Cat.No: T13896
Synonym:
Target: Others
Phosphatidic Acids (egg) (ammonium salt)
Cat.No: T37691
Synonym:
Target:
Urotensin II, mouse
Cat.No: TP1816
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T38141 Glycerophospholipids, cephalins

Phosphatidylethanolamines (egg)

Glycerophospholipids, cephalins (Phosphatidylethanolamines (egg)) 是一种从鸡蛋中分离出来的磷脂酰乙醇胺的混合物,在 sn-1和 sn-2位置有各种脂肪酰基。Glycerophospholipids, cephalins 完全水解可得到1mol 的甘油、磷酸、乙醇胺和2mol 的脂肪酸。Phosphatidylethanolamines 在膜融合和细胞分裂过程中收缩环的拆卸中起作用,可调节膜的弯曲度。Phosphatidylethanolamines 能够在没有任何蛋白质或核酸的帮助下传播传染性朊病毒。Phosphatidylethanolamines 在细菌膜中的主要作用之一是分散由阴离子膜磷脂引起的负电荷。
T79935 Forrestiacids J

ATP Citrate Lyase Metabolism
Forrestiacids J为一种特异性抑制ATP-柠檬酸裂解酶 (ACL) 的化合物,其IC50值为2.6 μM。
TN6639 Suspenoidside B

Suspenoidside B possesses strong hepatoprotective activities against the damage in HepG2 cell.
T79992 Sarglaroids F

Caspase Apoptosis; Proteases/Proteasome
Sarglaroids F(化合物6)为从草珊瑚根部提取的抗炎剂,影响K+外排并降低Caspase-1(P20)水平以抑制LPS/ATP诱导的IL-1β释放,对RAW264.7细胞无细胞毒性。
T80696 β-Acids colupulone

β-Acids colupulone为苦味化合物,可从啤酒花中提取分离。
T79936 Forrestiacids K

ATP Citrate Lyase Metabolism
Forrestiacids K, 萜类化合物,源自Pseudotsuga forrestii,作为ATP-citrate lyase (ACL) 的抑制剂。

天然产物

Glycerophospholipids, cephalins
Cat.No: T38141
Synonym: Phosphatidylethanolamines (egg)
Target:
Forrestiacids J
Cat.No: T79935
Synonym:
Target: ATP Citrate Lyase
Suspenoidside B
Cat.No: TN6639
Synonym:
Target:
Sarglaroids F
Cat.No: T79992
Synonym:
Target: Caspase
β-Acids colupulone
Cat.No: T80696
Synonym:
Target:
Forrestiacids K
Cat.No: T79936
Synonym:
Target: ATP Citrate Lyase
Cat. No. Product Name Species Expression System
TMPY-00828 Iduronate 2 sulfatase/IDS Protein, Human, Recombinant (His)

MPS2,IDS,SIDS,iduronate 2-sulfatase

Human HEK293 Cells
Iduronate 2-Sulfatase, also known as IDS, is a member of the highly conserved sulfatase family of enzymes that catalyze the hydrolysis of O- and N-sulfate esters from a variety of substrates. The human Iduronate 2-Sulfatase/IDS consists of a signal peptide, a propeptide, and a mature chain that may be further processed into two chains. Among the identified 18 human sulfatases, Iduronate 2-Sulfatase/IDS is required for the lysosomal degradation of the glycosaminoglycans (GAG), heparan sulfate, an...

重组蛋白

Iduronate 2 sulfatase/IDS Protein, Human, Recombinant (His)
Cat.No: TMPY-00828
Species: Human
Expression System: HEK293 Cells
TargetMol Loading
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