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Cat. No. Product Name Target Signaling Pathways
T29670 ADR-925

ICRF198,ICRF-198,ADR 925,ICRF 198,ADR925

Endogenous Metabolite Metabolism
ADR-925 (ICRF 198) 是右雷佐生的一种活性螯合铁代谢物,具有使新生大鼠心肌细胞免受阿霉素诱导的损伤的能力。
T22305 Dexrazoxane

右雷佐生,ICRF-187

Others Others
Dexrazoxane (ICRF-187) 是一种心脏保护剂。
T6467 Cardioxane

ADR-529 Hydrochloride,ICRF-187 hydrochloride,ADR-529,右雷佐生盐酸盐,Dexrazoxane HCl,Cardioxane hydrochloride,ICRF-187

Topoisomerase DNA Damage/DNA Repair
Cardioxane (ADR-529) 是一种心脏保护剂。
T69870 ICRF-193

Others Others
ICRF-193 is a DNA topoisomerase II inhibitor.
T69871 ICRF-196

Others Others
ICRF-196 is a Topoisomerase II Inhibitor and antineoplastic agent.
T25893 NU/ICRF 500

Others Others
NU/ICRF 500 is a novel anthracenyl-amino acid catalytic inhibitor of topoisomerase II.
T26047 Razoxane, (R)-

ICRF-186,ICRF186,NSC-169779,ICRF 186,NSC 169779

Others Others
Razoxane, (R)- shows antiangiogenic effects.
T26046 Razoxane

Topoisomerase DNA Damage/DNA Repair
Razoxane 是拓扑异构酶 II 的有效抑制剂,具有抗血管生成的作用,在肾细胞癌中具有研究价值。
T69869 Cyanabactin

Others Others
Cyanabactin is a novel ABA receptor agonist. It preferentially activates Pyrabactin Resistance 1 (PYR1) with low nanomolar potency.
T69936 NK314

Others Others
NK314 is a novel synthetic benzo[c]phenanthridine alkaloid that shows strong antitumor activity. It inhibited topoisomerase II activity and stabilized topoisomerase II-DNA cleavable complexes. The DNA breaks occurred within 1h after treatment with NK314 even without digestion of topoisomerase II by proteinase K, whereas etoposide required digestion of the enzyme protein in cleavable complex to detect DNA breaks. Pretreatment with topoisomerase II catalytic inhibitors, ICRF-193 and suramin, reduc...

化合物

ADR-925
Cat.No: T29670
Synonym: ICRF198,ICRF-198,ADR 925,ICRF 198,ADR925
Target: Endogenous Metabolite
Dexrazoxane
Cat.No: T22305
Synonym: 右雷佐生,ICRF-187
Target: Others
Cardioxane
Cat.No: T6467
Synonym: ADR-529 Hydrochloride,ICRF-187 hydrochloride,ADR-529,右雷佐生盐酸盐,Dexrazoxane HCl,Cardioxane hydrochloride,ICRF-187
Target: Topoisomerase
ICRF-193
Cat.No: T69870
Synonym:
Target: Others
ICRF-196
Cat.No: T69871
Synonym:
Target: Others
NU/ICRF 500
Cat.No: T25893
Synonym:
Target: Others
Razoxane, (R)-
Cat.No: T26047
Synonym: ICRF-186,ICRF186,NSC-169779,ICRF 186,NSC 169779
Target: Others
Razoxane
Cat.No: T26046
Synonym:
Target: Topoisomerase
Cyanabactin
Cat.No: T69869
Synonym:
Target: Others
NK314
Cat.No: T69936
Synonym:
Target: Others
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