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Search Results for " icam1 "
Targets Recommended: Integrin

5

抑制剂 & 化合物

12

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T14676 BMS-688521

Integrin Cytoskeletal Signaling
BMS-688521 是一种具有口服活性和高效性的 LFA-1/ICAM 相互作用抑制剂,是白细胞功能相关抗原-1 (LFA-1) 的小分子拮抗剂,具有潜在的抗炎活性。
T21781 A-286982

Integrin Cytoskeletal Signaling
A 286982是高效的LFA-1/ICAM-1相互作用变构抑制剂,在LFA-1/ICAM-1结合和LFA-1介导的细胞粘附实验中,其IC50分别为44和35 nM。
T2254 A-205804

Integrin Cytoskeletal Signaling
A-205804 是一种选择性口服有效的先导抑制剂,抑制 E-selectin 和 ICAM-1表达,IC50分别为 20 nM 和 25 nM,可用于慢性炎症疾病的研究。
T12783 RWJ 50271

Integrin Cytoskeletal Signaling
RWJ 50271 是具有口服活性的选择性LFA-1/ICAM-1相互作用抑制剂,抑制 LFA-1/ICAM-1 介导的细胞粘附,在细胞HL60中的IC50值为 5.0 μM。
T13147 ICAM-1-IN-1

Integrin Cytoskeletal Signaling
ICAM-1-IN-1 是选择性的 ICAM-1和 E-selectin 抑制剂,IC50值分别为5和7 nM。

化合物

BMS-688521
Cat.No: T14676
Synonym:
Target: Integrin
A-286982
Cat.No: T21781
Synonym:
Target: Integrin
A-205804
Cat.No: T2254
Synonym:
Target: Integrin
RWJ 50271
Cat.No: T12783
Synonym:
Target: Integrin
ICAM-1-IN-1
Cat.No: T13147
Synonym:
Target: Integrin
Cat. No. Product Name Species Expression System
TMPJ-00324 ICAM-1/CD54 Protein, Rhesus macaque, Recombinant (hFc)

Intercellular adhesion molecule 1,ICAM...

Rhesus HEK293 Cells
Intercellular adhesion molecule 1 (ICAM1) is known as CD54. ICAM-1 is constitutively present on endothelial cells, but its expression is increased by proinflammatory cytokines. The endothelial expression of ICAM-1 is increased in atherosclerotic and transplant-associated atherosclerotic tissue and animal models of atherosclerosis. Additionally, ICAM-1 has been implicated in the progression of autoimmune diseases. ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-...
TMPY-01142 ICAM-1/CD54 Protein, Human, Recombinant (His)

CD54,intercellular adhesion molecule 1,BB2,ICAM...

Human HEK293 Cells
ICAM-1/CD54 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 51 kDa and the accession number is A0A384MEK5.
TMPY-00981 ICAM-1/CD54 Protein, Human, Recombinant (aa 1-480,DDDDK)

CD54,ICAM-1,intercellular adhesion molecul...

Human HEK293 Cells
ICAM-1/CD54 Protein, Human, Recombinant (aa 1-480,DDDDK) is expressed in HEK293 mammalian cells. The predicted molecular weight is 50.2 kDa and the accession number is A0A384MEK5.
TMPK-00497 ICAM-1/CD54 Protein, Cynomolgus, Recombinant (His)

ICAM-1,CD54,BB2

Cynomolgus HEK293 Cells
Intercellular adhesion molecule-1 (ICAM-1; CD54) is a 90 kDa member of the immunoglobulin (Ig) superfamily and is critical for the firm arrest and transmigration of leukocytes out of blood vessels and into tissues. ICAM-1 is constitutively present on endothelial cells, but its expression is increased by proinflammatory cytokines. The endothelial expression of ICAM-1 is increased in atherosclerotic and transplant-associated atherosclerotic tissue and in animal models of atherosclerosis. ICAM-1/CD...
TMPK-00872 ICAM-1/CD54 Protein, Canine, Recombinant (His)

ICAM-1,CD54,BB2

Canine HEK293 Cells
Intercellular adhesion molecule-1 (ICAM-1; CD54) is a 90 kDa member of the immunoglobulin (Ig) superfamily and is critical for the firm arrest and transmigration of leukocytes out of blood vessels and into tissues. ICAM-1 is constitutively present on endothelial cells, but its expression is increased by proinflammatory cytokines. The endothelial expression of ICAM-1 is increased in atherosclerotic and transplant-associated atherosclerotic tissue and in animal models of atherosclerosis. ICAM-1/CD...
TMPY-06778 ICAM-1/CD54 Protein, Human, Recombinant (aa 1-480, LEVLFQ)

intercellular adhesion molecule 1,P3.58,ICAM

Human HEK293 Cells
ICAM-1/CD54 Protein, Human, Recombinant (aa 1-480, LEVLFQ) is expressed in HEK293 mammalian cells. The predicted molecular weight is 50.31 kDa and the accession number is NP_000192.2.
TMPY-05393 ICAM-1/CD54 Protein, Human, Recombinant (hFc)

P3.58,CD54,ICAM-1,BB2,intercellular adhesi...

Human HEK293 Cells
ICAM-1/CD54 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 76.2 kDa and the accession number is A0A384MEK5.
TMPY-06777 ICAM-1/CD54 Protein, Human, Recombinant (His & Avi), Biotinylated

intercellular adhesion molecule 1,P3.58,ICAM

Human HEK293 Cells
ICAM-1/CD54 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 52.77 kDa and the accession number is NP_000192.2.
TMPY-00825 ICAM-1/CD54 Protein, Human, Recombinant (His & hFc)

ICAM-1,BB2,CD54,P3.58,intercellular adhesi...

Human HEK293 Cells
ICAM-1/CD54 Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 77.4 kDa and the accession number is A0A384MEK5.
TMPH-01560 IL-26 Protein, Human, Recombinant (His & Trx)

Human E. coli
May play a role in local mechanisms of mucosal immunity and seems to have a proinflammatory function. May play a role in inflammatory bowel disease. Activates STAT1 and STAT3, MAPK1/3 (ERK1/2), JUN and AKT. Induces expression of SOCS3, TNF-alpha and IL-8, secretion of IL-8 and IL-10 and surface expression of ICAM1. Decreases proliferation of intestinal epithelial cells. Is inhibited by heparin. IL-26 Protein, Human, Recombinant (His & Trx) is expressed in E. coli expression system with N-6xHis-T...
TMPH-01559 IL-26 Protein, Human, Recombinant (His)

Human P. pastoris (Yeast)
May play a role in local mechanisms of mucosal immunity and seems to have a proinflammatory function. May play a role in inflammatory bowel disease. Activates STAT1 and STAT3, MAPK1/3 (ERK1/2), JUN and AKT. Induces expression of SOCS3, TNF-alpha and IL-8, secretion of IL-8 and IL-10 and surface expression of ICAM1. Decreases proliferation of intestinal epithelial cells. Is inhibited by heparin. IL-26 Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecula...
TMPJ-00432 GITR Ligand/TNFSF18 Protein, Cynomolgus, Recombinant (His)

GITRL,TNFSF18,Activation-inducible TNF-related liga...

Cynomolgus HEK293 Cells
TNFSF18 is a single-pass type II membrane protein. It is expressed at high levels in the small intestine, ovary, testis, kidney and endothelial cells. TNFSF18 cytokine binds to TNFRSF18/AITR/GITR. It regulates T-cell responses, and functions as costimulator and lower the threshold for T-cell activation and T-cell proliferation. It is Important for interactions between activated T-lymphocytes and endothelial cells and Promotes leukocyte adhesion to endothelial cells. TNFSF18 mediates activation ...

重组蛋白

ICAM-1/CD54 Protein, Rhesus macaque, Recombinant (hFc)
Cat.No: TMPJ-00324
Species: Rhesus
Expression System: HEK293 Cells
ICAM-1/CD54 Protein, Human, Recombinant (His)
Cat.No: TMPY-01142
Species: Human
Expression System: HEK293 Cells
ICAM-1/CD54 Protein, Human, Recombinant (aa 1-480,DDDDK)
Cat.No: TMPY-00981
Species: Human
Expression System: HEK293 Cells
ICAM-1/CD54 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPK-00497
Species: Cynomolgus
Expression System: HEK293 Cells
ICAM-1/CD54 Protein, Canine, Recombinant (His)
Cat.No: TMPK-00872
Species: Canine
Expression System: HEK293 Cells
ICAM-1/CD54 Protein, Human, Recombinant (aa 1-480, LEVLFQ)
Cat.No: TMPY-06778
Species: Human
Expression System: HEK293 Cells
ICAM-1/CD54 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-05393
Species: Human
Expression System: HEK293 Cells
ICAM-1/CD54 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-06777
Species: Human
Expression System: HEK293 Cells
ICAM-1/CD54 Protein, Human, Recombinant (His & hFc)
Cat.No: TMPY-00825
Species: Human
Expression System: HEK293 Cells
IL-26 Protein, Human, Recombinant (His & Trx)
Cat.No: TMPH-01560
Species: Human
Expression System: E. coli
IL-26 Protein, Human, Recombinant (His)
Cat.No: TMPH-01559
Species: Human
Expression System: P. pastoris (Yeast)
GITR Ligand/TNFSF18 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPJ-00432
Species: Cynomolgus
Expression System: HEK293 Cells
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