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15

抑制剂 & 化合物

1

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Cat. No. Product Name Target Signaling Pathways
TP1155L Human growth hormone-releasing factor acetate

GHSR GPCR/G Protein
Human growth hormone-releasing factor acetate 是一种下丘脑多肽,通过与垂体前叶细胞上的 GHRH 受体 (GHRHR) 结合来刺激 GH 的产生和释放。
TP1155 Human growth hormone-releasing factor

Growth Hormone Releasing Factor human

Human growth hormone-releasing factor stimulates GH production and release by binding to the GHRH Receptor (GHRHR) on cells in the anterior pituitary.Growth hormone-releasing hormone is a hormone produced in the hypothalamus. The main role of growth hormo
T34684 Somatotropin (6-13)

Human growth hormone (6-13)

Somatotropin (6-13) is a growth hormone.
T75713 Human growth hormone-releasing factor TFA

Growth Hormone Releasing Factor human TFA 是下丘脑多肽,通过与GHRHR结合,刺激生长激素生成和释放。
T7815L AOD9604 acetate(221231-10-3 free base)

AOD-9604 acetate,AOD9604 acetate,AOD 9604 acetate

Others Others
AOD9604 acetate(221231-10-3 free base) 是一种基于人类生长激素的潜在抗肥胖肽。
T76317 [His1,Nle27] GHRF (1-32), amide, human

[His1,Nle27] GHRF (1-32), amide, human为一种生长激素释放激素(GHRH)类似物,对GHRHR受体具有较好的亲和力。
TP1157 GLP-2(1-33)(human)

GLP-2 (human),Glucagon-like peptide 2 (human)

GLP-2(1-33) (human) is an enteroendocrine hormone which stimulates the growth of the intestinal epithelium.
T83549 (D-Ala2)-GRF (1-29) amide (human)

'(D-Ala2)-GRF (1-29) amide (human)' 为一种GRF的超激动剂,其GH释放活性在猪和大鼠体内极为显著,大约为GRF (1-29)活性的50倍。
T78039 Acetyl-(D-Arg2)-GRF (1-29) amide (human)

Acetyl-(D-Arg2)-GRF (1-29) amide (human) 是一种针对人体的生长激素释放因子(GRF)拮抗剂,其主要作用是抑制生长激素(GH)的释放,广泛应用于内分泌学领域的研究。
TP1302 Somatostatin

Somatostatin, also known as growth hormone-inhibiting hormone, is a naturally-occurring peptide hormone of 14 or 28 amino acid residues that regulates the endocrine system. It is secreted by the D cells of the islets to inhibit the release of insulin and
T83756 S1H TFA

Site 1-binding Helix

S1H是一种人造肽类模拟物,模仿人类生长激素的第36至51个氨基酸,且为生长激素受体的拮抗剂。在溶液中呈现α-螺旋结构,并在100和200纳摩尔(nM)的浓度下,能降低SK-MEL-28和MALME-3M黑色素瘤细胞系以及IM-9 B细胞淋巴细胞中,由人类生长激素及泌乳素诱导的STAT5磷酸化。
T73702 Mecasermin

Mecasermin(Human IGF-I; FK 780),一种重组人胰岛素样生长因子I(IGF-I),主要用于研究因生长激素(GH)受体缺陷或GH抑制抗体导致的GH不敏感性而引起的生长障碍。
T61747 TTA-P1

TTA-P1 is a highly potent compound that effectively inhibits human T-type calcium channels, which are involved in various physiological processes such as neuronal burst firing, hormone secretion, and cell growth. With its unique state-independent properties, TTA-P1 holds promising potential for advancing research on absence epilepsy [1].
T68249 IRC-083927 HCl

IRC-083927 HCl is novel and potent microtubule inhibitor with potential anticancer activity. IRC-083927 inhibits the tubulin polymerization by a binding to the colchicine site. IRC-083927 inhibits in vitro cell growth of human cancer cell lines in the low nanomolar range. More interesting, it remains highly active against cell lines resistant to microtubule-interacting agents (taxanes, Vinca alkaloids, or epothilones). Chronic oral treatment with IRC-083927 (5 mg/kg) inhibits the growth of two h...
T76660 pTH (1-37) (human)

pTH (1-37) (human) 为甲状旁腺激素(PTH)的一段,能诱导cAMP产生并提升碱性磷酸酶活性,进而增强尿毒症动物的生长速度、骨钙含量及骨矿物质密度(BMD),显示出对骨质疏松症研究的应用潜力。

化合物

Human growth hormone-releasing factor acetate
Cat.No: TP1155L
Synonym:
Target: GHSR
Human growth hormone-releasing factor
Cat.No: TP1155
Synonym: Growth Hormone Releasing Factor human
Target:
Somatotropin (6-13)
Cat.No: T34684
Synonym: Human growth hormone (6-13)
Target:
Human growth hormone-releasing factor TFA
Cat.No: T75713
Synonym:
Target:
AOD9604 acetate(221231-10-3 free base)
Cat.No: T7815L
Synonym: AOD-9604 acetate,AOD9604 acetate,AOD 9604 acetate
Target: Others
[His1,Nle27] GHRF (1-32), amide, human
Cat.No: T76317
Synonym:
Target:
GLP-2(1-33)(human)
Cat.No: TP1157
Synonym: GLP-2 (human),Glucagon-like peptide 2 (human)
Target:
(D-Ala2)-GRF (1-29) amide (human)
Cat.No: T83549
Synonym:
Target:
Acetyl-(D-Arg2)-GRF (1-29) amide (human)
Cat.No: T78039
Synonym:
Target:
Somatostatin
Cat.No: TP1302
Synonym:
Target:
S1H TFA
Cat.No: T83756
Synonym: Site 1-binding Helix
Target:
Mecasermin
Cat.No: T73702
Synonym:
Target:
TTA-P1
Cat.No: T61747
Synonym:
Target:
IRC-083927 HCl
Cat.No: T68249
Synonym:
Target:
pTH (1-37) (human)
Cat.No: T76660
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T3S0860 Gitogenin

UGT Metabolism
Gitogenin 是一种从Tribulus longipetalus 整株中分离出来的天然类固醇,是一种 UDP-葡萄糖醛酸转移酶 1A4 (UGT1A4) 和 α-葡萄糖苷酶的选择性抑制剂,其IC50分别为 0.69 µM (使用三氟拉嗪为底物) 和 37.2 μM,对人类主要细胞色素 P450 亚型的活性无抑制作用。

天然产物

Gitogenin
Cat.No: T3S0860
Synonym:
Target: UGT
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