Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T0025 |
Haloperidol
Aloperidin,氟哌啶醇,Serenace,Haldol |
Dopamine Receptor; 5-HT Receptor | GPCR/G Protein; Neuroscience |
Haloperidol (Serenace) 是一种安定药,是一种dopamine D2 receptor 拮抗剂。 | |||
T25487 |
Haloperidol decanoate
KD 16,KD-136,KD 136,Neoperidole,Haldol |
Others | Others |
Haloperidol decanoate (KD 16) 是一种典型的抗精神病药物,用作精神分裂症和情绪障碍的维持治疗,配制成用于肌肉注射的酯。 | |||
T11536 |
Haloperidol (D4')
Haloperidol D4',氟哌啶醇 (D4') |
Others | Others |
Haloperidol D4' is deuterium-labeled haloperidol. Haloperidol is a dopamine D2 receptor antagonist. | |||
T37167 |
Reduced Haloperidol
|
||
Reduced haloperidol is an active metabolite of haloperidol . It is formed via reduction of haloperidol by ketone reductase. Reduced haloperidol inhibits radioligand binding to sigma-1 and dopamine D2 receptors (Kis = 1.4 and 31 nM, respectively) and stimulates brain-derived neurotrophic factor (BDNF) secretion from CCF-SSTG1 and U87MG astrocytic glial cells. It also inhibits norepinephrine, dopamine, and serotonin (5-HT) reuptake (Kis = 21, 25, and 33 μM, respectively, in COS-7 cells expressing ... | |||
T11535 |
Haloperidol D4
氟哌啶醇D4 |
Others | Others |
Haloperidol D4 is deuterium-labeled haloperidol. | |||
T21669 | Haloperidol hydrochloride | ||
Haloperidol hydrochloride 是一种有效的 dopamine D2 receptor 拮抗剂,广泛用作抗精神病药 | |||
T62975 |
Haloperidol lactate
|
||
Haloperidol lactate 是一种有效的抗精神病药。Haloperidol lactate 具有潜力进行精神障碍的研究。Haloperidol lactate 能够用于急性和慢性精神分裂症和多发性秽语综合征。 | |||
T0280 |
Spiperone
螺哌隆,Spiroperidol,Spiropitan |
Dopamine Receptor | GPCR/G Protein; Neuroscience |
Spiperone (Spiropitan) 是多巴胺 D2、血清素5-HT1A 和血清素5-HT2A 拮抗剂。它是广泛使用的药理学工具。它具有研究神经系统疾病的潜力。 | |||
T33868 |
Palmitoyl glutamic acid
N-Palmitoyl-L-glutamic acid,Palmitoylglutaminic acid |
||
Palmitoyl glutamic acid (N-Palmitoyl-L-glutamic acid) 是一种酰基氨基酸,可阻断主动脉收缩,可拮抗由氟哌啶醇诱发的口腔运动障碍。Palmitoyl glutamic acid 常常添加在化妆品中。 | |||
T29139 |
VU0477886
VU-0477886,VU 0477886 |
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VU0477886 is a potent mGlu4 positive allosteric modulator (PAM) with robust efficacy in a standard preclinical Parkinson's disease model, haloperidol-induced catalepsy (HIC). | |||
T63428 |
Antibacterial agent 67
|
||
Antibacterial agent 67 能够显著抑制琥珀酸脱氢酶的活性,IC50 值为 0.03 μM,且对琥珀酸脱氢酶的酶抑制活性显著比氟哌啶醇(IC50= 4.40 μM)高。 | |||
T37478 |
Acetyl β-Endorphin (1-26) (human) (trifluoroacetate salt)
|
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Acetyl β-endorphin (1-26) is a neuropeptide found in rat hippocampus, brain stem, and pituitary. It is also present in the human hypothalamus, where it comprises approximately 4.9% of total β-endorphin peptides. Acetyl β-endorphin (1-26) is produced through posttranslational processing of β-endorphin and is processed similarly in rat and human hypothalamus. Levels of acetyl β-endorphin (1-26) increase in the rat pars intermedia and brain stem following chronic administration of haloperidol . | |||
T83523 | (S)-(-)-MRJF22 | ||
(S)-(-)-MRJF22为氟哌啶醇代谢物II丙戊酸酯,展现了强效的抗迁移活性,尤其在内皮细胞和肿瘤细胞中。作为一种多功能活性分子,(S)-(-)-MRJF22对葡萄膜黑色素瘤具有潜在疗效。 | |||
T70049 |
Ro 04-5595 free base
|
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Ro 04-5595 is a selective antagonist of NMDA receptors NR2B subunits. Ro 04-5595 had an EC 50 of 186 ± 32 nmol/L. Ro 04-5595 was predicted to bind the EVT-101 binding site, not the ifenprodil-binding site. Specific binding, defined with a new NR2B-specific antagonist Ro 04-5595 at 10 microM was fully inhibited by several compounds with the following rank order of affinities--Ro 25-6981 > CP-101,606 > Ro 04-5595 = ifenprodil >> eliprodil > haloperidol > spermine > spermidine > MgCl2 > CaCl2--and... |