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抑制剂 & 化合物

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重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T39631 Chst15-IN-1

Chst15-IN-1

Chst15-IN-1 is a powerful, reversible, covalent inhibitor of the Chst15 enzyme. It effectively suppresses the sulfation levels of chondroitin sulfate-E (CS-E) and other closely related sulfotransferases responsible for glycosaminoglycans (GAGs) synthesis. Acting as a selective sulfotransferase inhibitor, Chst15-IN-1 can attenuate the inhibitory actions of chondroitin sulfate proteoglycans (CSPGs), making it a promising candidate for enhancing neuronal repair.

化合物

Chst15-IN-1
Cat.No: T39631
Synonym: Chst15-IN-1
Target:
Cat. No. Product Name Species Expression System
TMPY-05004 FGF-4 Protein, Human, Recombinant

HST-1,KFGF,fibroblast growth factor 4,...

Human E. coli
FGF (fibroblast growth factor) signalling is known to be required for many aspects of mesoderm formation and patterning during Xenopus development and has been implicated in regulating genes required for the specification of both blood and skeletal muscle lineages. Fibroblast growth factor 4 (FGF4) signaling induces differentiation from embryonic stem cells (ESCs) via the phosphorylation of downstream molecules such as mitogen-activated protein kinase/extracellular signal-related kinase (MEK) a...
TMPJ-00835 FGF-4 Protein, Mouse, Recombinant

HSTF1,HST-1,FGF4,FGF-4,H...

Mouse E. coli
Fibroblast growth factor 4(FGF-4) is a heparin binding member of the FGF family. The human FGF4 cDNA encodes 206 amino acids (aa) with a 33 aa signal sequence and a 173 aa mature protein with an FGF homology domain that contains a heparin binding region near the C-terminus. Mature human FGF4 shares 91%, 82%, 94% and 91% aa identity with mouse, rat, canine and bovine FGF4, respectively. Human FGF-4 has been shown to exhibit cross species activity. Expression of FGF-4 and its receptors, FGF R1c, 2...
TMPY-03959 CHST11 Protein, Human, Recombinant (His)

carbohydrate (chondroitin 4) sulfotransferase 1...

Human Baculovirus Insect Cells
CHST11, also known as C4ST-1, belongs to the sulfotransferase 2 family. CHST11 localizes to the golgi membrane, and catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage, and is distributed on the surfaces of many cells and extracellular matrices. A chromosomal translocation involving CHST11 gene and IgH, t(12;14)(q23;q32), has been reported in a patient with ...
TMPY-01707 CHST15 Protein, Human, Recombinant (His)

BRAG,carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulf...

Human HEK293 Cells
Carbohydrate sulfotransferase 15, also known as N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase, GalNAc4S-6ST, B-cell RAG-associated gene protein, CHST15 and BRAG, is a single-pass type II membrane protein which belongs to thesulfotransferase 1 family. CHST15 / BRAG is expressed in B-cell-enriched tissues but not in fetal or adult thymus. It is expressed in fetal and adult spleen, lymph node, tonsil, bone marrow and peripheral leukocytes. It is not expressed in T-cells. In pro-B, pre...

重组蛋白

FGF-4 Protein, Human, Recombinant
Cat.No: TMPY-05004
Species: Human
Expression System: E. coli
FGF-4 Protein, Mouse, Recombinant
Cat.No: TMPJ-00835
Species: Mouse
Expression System: E. coli
CHST11 Protein, Human, Recombinant (His)
Cat.No: TMPY-03959
Species: Human
Expression System: Baculovirus Insect Cells
CHST15 Protein, Human, Recombinant (His)
Cat.No: TMPY-01707
Species: Human
Expression System: HEK293 Cells
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