Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T32090 |
HMS-I2
HMSI2,HMS I2 |
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HMS-I2 is a chemical probe used to form heterochromatin. It works by disrupting heterochromatin mediated transcriptional gene silencing. | |||
T32089 |
HMS-I1 Hydrobromide
HMS-I1 HBr |
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HMS-I1 Hydrobromide is a probe that works by destroying heterochromatin mediated transcriptional gene silencing and is used for studies of heterochromatin formation and function. | |||
T15159 |
Dorzagliatin
HMS5552 |
Glucokinase | Metabolism |
Dorzagliatin (HMS5552) 是双重作用的葡萄糖激酶 (glucokinase;GK) 激活剂,可改善 2 型糖尿病的血糖控制,提高胰腺 β 细胞功能。 | |||
T28781 |
Sinogliatin
HMS-5552,RO 5305552,HMS5552,RO5305552,HMS 5552,RO-5305552 |
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Sinogliatin, a glucokinase activator, is used potentially for the treatment of type 2 diabetes. | |||
T69365 | HMS607P03 | ||
HMS607P03 is an activator of SIRT1 which induces autophagic cell death via the AMPK-mTOR-ULK complex and induces mitophagy by the SIRT1-PINK1-Parkin pathway. HMS607P03 downregulates 14-3-3γ, catalase, profilin-1, and HSP90α. | |||
T0977 |
Medrysone
Gimeracil,6α-Methyl-11β-hydroxyprogesterone,6A-甲基-11B-羟孕酮,甲羟松 |
Glucocorticoid Receptor; Others | Endocrinology/Hormones; Others |
Medrysone (6α-Methyl-11β-hydroxyprogesterone) 是局部合成的糖皮质激素,具有代谢、抗炎和抗过敏特性,有潜力用于眼科的眼炎症研究。 |