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6

抑制剂 & 化合物

1

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T32090	HMS-I2 HMSI2,HMS I2
	HMS-I2 is a chemical probe used to form heterochromatin. It works by disrupting heterochromatin mediated transcriptional gene silencing.
T32089	HMS-I1 Hydrobromide HMS-I1 HBr
	HMS-I1 Hydrobromide is a probe that works by destroying heterochromatin mediated transcriptional gene silencing and is used for studies of heterochromatin formation and function.
T28781	Sinogliatin HMS-5552,RO 5305552,HMS5552,RO5305552,HMS 5552,RO-5305552
	Sinogliatin, a glucokinase activator, is used potentially for the treatment of type 2 diabetes.
T15159	Dorzagliatin HMS5552	Glucokinase	Metabolism
	Dorzagliatin (HMS5552) 是双重作用的葡萄糖激酶 (glucokinase;GK) 激活剂，可改善 2 型糖尿病的血糖控制，提高胰腺 β 细胞功能。
T69365	HMS607P03
	HMS607P03 is an activator of SIRT1 which induces autophagic cell death via the AMPK-mTOR-ULK complex and induces mitophagy by the SIRT1-PINK1-Parkin pathway. HMS607P03 downregulates 14-3-3γ, catalase, profilin-1, and HSP90α.
T0977	Medrysone Gimeracil,6α-Methyl-11β-hydroxyprogesterone,6A-甲基-11B-羟孕酮,甲羟松	Glucocorticoid Receptor; Others	Endocrinology/Hormones; Others
	Medrysone (6α-Methyl-11β-hydroxyprogesterone) 是局部合成的糖皮质激素，具有代谢、抗炎和抗过敏特性，有潜力用于眼科的眼炎症研究。

化合物

Cat.No: T32090

Synonym: HMSI2,HMS I2

HMS-I1 Hydrobromide

Cat.No: T32089

Synonym: HMS-I1 HBr

Cat.No: T28781

Synonym: HMS-5552,RO 5305552,HMS5552,RO5305552,HMS 5552,RO-5305552

Cat.No: T15159

Synonym: HMS5552

Target: Glucokinase

Cat.No: T69365

Cat.No: T0977

Synonym: Gimeracil,6α-Methyl-11β-hydroxyprogesterone,6A-甲基-11B-羟孕酮,甲羟松

Target: Glucocorticoid Receptor, Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-00732	Cathepsin C Protein, Human, Recombinant (His) DPP-I,PLS,JP,cathepsin C,CPPI,DPPI,PDON1,PALS,DPP1,JPD,H...	Human	HEK293 Cells
	Cathepsins are proteases found in many types of cells conserved in all animals, which have a vital role in mammalian cellular turnover such as bone resorption. The lysosomal cysteine protease Cathepsin C (CTSC), also known as dipeptidyl peptidase I (DPPI/DPP1), activates a number of granule-associated serine proteases with pro-inflammatory and immune functions by removal of their inhibitory N-terminal dipeptides. This lysosomal exo-cysteine protease belonging to the peptidase C1 family. Active c...

重组蛋白

Cathepsin C Protein, Human, Recombinant (His)

Cat.No: TMPY-00732

Species: Human

Expression System: HEK293 Cells

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